L3MBTL4 Inhibitors
The class of chemical compounds known as Lethal(3)malignant brain tumor-like protein 4 Inhibitors encompasses a diverse set of molecules that share a common potential ability to affect the expression or activity of the Lethal(3)malignant brain tumor-like protein 4. This protein, as a putative Polycomb group (PcG) protein, plays a pivotal role in maintaining a transcriptionally repressive state of genes via probable chromatin modification, which is heritably altered in its expressibility.
The compounds in this class largely exert their potential inhibitory effects by interacting with the chromatin remodeling processes or the broader epigenetic landscape. Their modes of action vary, with some targeting DNA methylation, some affecting histone modifications, and others interfering with associated protein functionalities. Regardless of the mechanism, the overarching effect of these compounds is a potential alteration in the chromatin state or the associated machinery, which, in turn, could impact the normal function of the Lethal(3)malignant brain tumor-like protein 4. The exact interaction and specificity of these compounds with the protein and its pathways would need extensive research and characterization.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $79.00 $300.00 | 32 | |
Parthenolide might interfere with the chromatin remodeling processes guided by Polycomb group (PcG) proteins, thus potentially affecting the repressive activity of Lethal(3)malignant brain tumor-like protein 4. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can modulate epigenetic changes, which might indirectly inhibit the expression or activity of Lethal(3)malignant brain tumor-like protein 4, a putative PcG protein. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, found in green tea, is known for its potential to affect epigenetic modifications. This may lead to an altered activity of PcG proteins like Lethal(3)malignant brain tumor-like protein 4. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor. It might affect the epigenetic landscape that PcG proteins, including Lethal(3)malignant brain tumor-like protein 4, aim to establish or maintain. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has potential epigenetic modulating properties that could alter the activity or expression of PcG proteins like Lethal(3)malignant brain tumor-like protein 4. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 influences the bromodomain-containing proteins. It might indirectly affect the chromatin state, potentially impacting the function of PcG proteins like Lethal(3)malignant brain tumor-like protein 4. | ||||||
Garcinol | 78824-30-3 | sc-200891 sc-200891A | 10 mg 50 mg | $136.00 $492.00 | 13 | |
Garcinol can inhibit histone acetyltransferases, potentially influencing chromatin states that PcG proteins, including Lethal(3)malignant brain tumor-like protein 4, work upon. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $36.00 $110.00 $400.00 | ||
BIX-01294 is a G9a histone methyltransferase inhibitor. It might modify the chromatin landscape, potentially affecting the function of PcG proteins like Lethal(3)malignant brain tumor-like protein 4. | ||||||
3-Deazaneplanocin, HCl salt | 120964-45-6 | sc-351856 sc-351856A sc-351856B | 1 mg 5 mg 10 mg | $251.00 $600.00 $918.00 | 2 | |
DZNep depletes EZH2, a component of PRC2 complex. This could potentially influence other PcG proteins, including Lethal(3)malignant brain tumor-like protein 4. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin's potential in modulating epigenetic processes might indirectly influence the expression or activity of PcG proteins, including Lethal(3)malignant brain tumor-like protein 4. | ||||||