Keratin-associated protein 10-10 (KRTAP10-10) is a member of a family of proteins known as keratin-associated proteins (KAPs), which are encoded by a cluster of genes within the KRTAP gene family. This protein is expressed in the hair follicles and is an integral component of hair fibers.KRTAP10-10 is characterized by its high cysteine content, which is a hallmark of many KAPs. This high cysteine content allows for the formation of a large number of disulfide bonds, contributing to the extensive cross-linking with other hair proteins, particularly keratins. These disulfide bonds are critical for providing the structural rigidity and resilience typical of hair fibers. Consequently, KRTAP10-10 plays a significant role in determining the physical properties of hair, such as strength, flexibility, and response to humidity.
The precise amino acid sequence and structure of KRTAP10-10, as well as its interactions with other proteins like keratins, affect the texture and quality of hair. Variations in the KRTAP genes can lead to differences in hair texture between individuals and across different populations.Research on KRTAP10-10 and other KAPs extends to understanding the genetic basis of hair disorders as well as normal hair variation. Mutations or alterations in the expression of KRTAPs may result in changes to hair structure that can manifest as hair disorders.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Minoxidil (U-10858) | 38304-91-5 | sc-200984 sc-200984A | 100 mg 1 g | $68.00 $344.00 | ||
Promotes hair growth and might indirectly affect the expression or function of KRTAP10-10 in hair follicles. | ||||||
Finasteride | 98319-26-7 | sc-203954 | 50 mg | $103.00 | 3 | |
A 5α-reductase inhibitor, used to treat hair loss, could influence hair follicle biology and potentially KRTAP10-10 activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Involved in cellular growth and differentiation, possibly impacting hair follicle development and KRTAP10-10. | ||||||
D-(+)-Biotin | 58-85-5 | sc-204706 sc-204706A sc-204706B | 1 g 5 g 25 g | $40.00 $105.00 $326.00 | 1 | |
A vitamin associated with hair and nail health, could indirectly affect KRTAP10-10 through improved hair follicle health. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $107.00 | 3 | |
Used for hair loss treatment, might have indirect effects on KRTAP10-10 through its action on hair follicles. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Plays a role in skin and hair follicle health, potentially influencing KRTAP10-10 indirectly. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Immunosuppressant with hair growth-promoting effects, could indirectly affect KRTAP10-10 function. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $102.00 $423.00 | ||
An omega-3 fatty acid, known for its positive effects on skin and hair health, potentially affecting KRTAP10-10. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Essential for hair tissue growth and repair, might influence KRTAP10-10 activity. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Sometimes used in hair loss treatments, might indirectly affect hair follicle health and KRTAP10-10 function. |