Date published: 2026-4-23

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KLC2 Inhibitors

KLC2 inhibitors constitute a specialized category of chemical compounds that have garnered attention in the field of molecular biology and cellular transport research. KLC2, or Kinesin Light Chain 2, is a protein that plays a pivotal role in intracellular transport processes, specifically in facilitating the movement of cargo along microtubules within cells. KLC2 inhibitors is a group of molecules meticulously designed to selectively target and modulate the activity of KLC2. These inhibitors serve as invaluable tools in laboratory investigations, enabling researchers to explore the intricate molecular functions and cellular processes associated with KLC2. KLC2 inhibitors typically function by interfering with the interactions between KLC2 and its binding partners, such as kinesin heavy chains and cargo molecules. This interference can disrupt the normal process of cargo transport along microtubules, impacting various aspects of intracellular trafficking and cellular function. Researchers employ KLC2 inhibitors to gain insights into the physiological roles and molecular interactions of KLC2 within cells, aiming to advance our understanding of the fundamental mechanisms involved in intracellular transport. Through the study of KLC2 inhibitors, scientists seek to unravel the complexities of cellular logistics, molecular motor proteins, and the broader field of cell biology, contributing to our knowledge of how cells precisely orchestrate the movement of essential materials and organelles within their confines.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This compound can inhibit DNA methyltransferases, potentially leading to reduced methylation and altered gene expression which might affect KLC2 expression levels.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

As an inhibitor of histone deacetylases, it may alter chromatin structure and influence the transcription of various genes, potentially including KLC2.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid can modulate gene expression through its receptors, potentially affecting transcription factors that regulate KLC2.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

This mTOR inhibitor can lead to altered protein synthesis and gene expression profiles, which may include downregulation of KLC2 expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

By inhibiting PI3K, this compound can affect downstream signaling pathways that may influence KLC2 expression.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

An inhibitor of JNK signaling, which could indirectly affect transcription factors and gene expression patterns including KLC2.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

This MEK inhibitor may impact MAPK/ERK pathway and alter transcriptional regulation of various genes, possibly affecting KLC2 expression.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAPK, potentially affecting the expression of genes regulated by this pathway including KLC2.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

As a specific inhibitor of MEK, it can interfere with ERK pathway signaling and potentially modulate gene expression, including KLC2.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

A PI3K inhibitor that can modify multiple signaling pathways and potentially change the expression profile of genes like KLC2.