KIAA0513 Activators
Forskolin, by increasing cAMP, can trigger protein kinase A and initiate a domino effect that cascades through various signaling pathways, potentially influencing the expression and function of a broad spectrum of proteins. Similarly, Phorbol 12-myristate 13-acetate acts upon protein kinase C, a pivotal player in cell signaling that can alter the behavior of proteins within the cell. Histone deacetylase inhibitors like Sodium Butyrate and Trichostatin A exert their impact on the epigenetic landscape, reconfiguring chromatin architecture to facilitate a transcriptional environment that could enhance the expression of numerous proteins. The DNA methyltransferase inhibitor 5-Azacytidine shifts the methylation patterns on DNA, altering the transcriptional activity of genes, which may encompass the regulatory sequences of proteins like KIAA0513.
Polyphenols such as Epigallocatechin gallate and Resveratrol operate through modulation of signaling pathways and activation of sirtuins, respectively, both of which carry implications for gene expression and protein functionality. LY294002 and Rapamycin interface with the PI3K/AKT and mTOR pathways, central conduits of cell growth and protein synthesis, while SP600125, PD98059, and SB203580 target the JNK and MAPK/ERK pathways, which are integral to cellular responses and the regulation of protein expression.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC) which can modulate protein function and expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Histone deacetylase inhibitor, can lead to a more relaxed chromatin structure and thus influence gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Another histone deacetylase inhibitor, which can affect gene expression and protein function. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, can lead to changes in DNA methylation status and subsequently alter gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol that can modulate various signaling pathways and potentially affect gene expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Influences sirtuin activity and can modify gene expression patterns. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, can alter AKT signaling and thus influence various cellular functions including protein expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR signaling, which is known to influence protein synthesis and cellular growth. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK), can affect cell signaling and protein expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor, can alter MAPK/ERK signaling and potentially impact protein function and expression. | ||||||