KIAA0513 inhibitors represent a class of compounds that specifically target and modulate the activity of the KIAA0513 protein. The KIAA0513 gene encodes a protein whose function is still being characterized, but it is believed to be involved in cellular processes related to neurodevelopment and signal transduction pathways. Inhibitors of this protein are designed to disrupt or block its interaction with various molecular partners or pathways, leading to alterations in cellular signaling dynamics. These inhibitors are often small molecules that can bind to specific domains of the KIAA0513 protein, preventing it from carrying out its normal cellular roles. The structure of KIAA0513 inhibitors is typically designed based on an understanding of the protein's three-dimensional conformation and active sites, allowing for precise targeting of its functional regions.
KIAA0513 inhibitors are usually studied in molecular biology and cell biology to better understand the role of the KIAA0513 protein in various cellular functions. By inhibiting its activity, researchers can explore the downstream effects on signal transduction pathways and gene expression profiles. These inhibitors are valuable tools in elucidating the molecular mechanisms underlying cellular processes in which KIAA0513 is implicated. They can also help in defining the structural features of the protein that are essential for its activity, enabling the identification of key residues or motifs necessary for its interaction with other proteins or cellular components. This, in turn, aids in the development of a deeper understanding of the protein's biological roles and its potential involvement in complex cellular networks.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GDC-0941 | 957054-30-7 | sc-364498 sc-364498A | 5 mg 10 mg | $184.00 $195.00 | 2 | |
Targets the PI3K pathway, which could indirectly reduce the activity of KIAA0513 if it is part of this signaling cascade. | ||||||
Selumetinib | 606143-52-6 | sc-364613 sc-364613A sc-364613B sc-364613C sc-364613D | 5 mg 10 mg 100 mg 500 mg 1 g | $28.00 $80.00 $412.00 $1860.00 $2962.00 | 5 | |
Interferes with the MAPK pathway, potentially altering signaling cascades that KIAA0513 may be involved in, leading to decreased protein activity. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Inhibits the proteasome, which might affect the degradation of KIAA0513 or its substrate proteins, thereby modulating its function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Acts on the mTOR pathway, which could influence KIAA0513 activity if there is a connection between mTOR signaling and KIAA0513 function. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor, which can alter chromatin structure and gene expression, potentially affecting the expression levels of KIAA0513. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Disrupts calcium homeostasis in the endoplasmic reticulum, which might influence KIAA0513 activity if it is calcium-dependent. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor, which could lead to a decrease in KIAA0513 activity by modulating the PI3K/AKT pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, which is part of the MAPK pathway, potentially impacting KIAA0513 if it is associated with this signaling route. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, which could affect KIAA0513 activity if there is linkage between JNK signaling and KIAA0513's role in the cell. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Targets p38 MAPK, which might modulate KIAA0513 activity if p38 MAPK signaling is relevant to the function or regulation of KIAA0513. | ||||||