Date published: 2026-5-30

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κ-Actin Inhibitors

κ-Actin Inhibitors constitute a specialized class of chemical compounds designed to selectively impede the activity of κ-actin, a variant of the actin protein. Actin proteins are essential components of the cytoskeleton, contributing to cellular structure, motility, and intracellular transport. κ-Actin, a specific isoform within the actin family, exhibits unique structural and functional features. The development of inhibitors targeting κ-actin is crucial for scientific investigations, providing researchers with specific tools to explore the molecular functions and regulatory roles associated with this particular actin variant.

The synthesis and optimization of κ-Actin Inhibitors require a detailed understanding of the isoform's structural characteristics and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of κ-actin and interfere with its normal cytoskeletal functions. By employing κ-Actin Inhibitors in experimental settings, researchers can explore the consequences of isoform-specific inhibition on cellular processes, shedding light on the specific substrates and molecular pathways influenced by κ-actin. The study of κ-Actin Inhibitors contributes to the broader exploration of cytoskeletal dynamics, providing insights into the intricate molecular machinery that underlies fundamental cellular functions related to cell shape, movement, and structural integrity, with a specific focus on the unique properties of the κ-actin isoform.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Actinomycin D binds to DNA, inhibiting transcription and preventing the synthesis of κ-Actin mRNA.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Cycloheximide disrupts protein synthesis, leading to a reduction in κ-Actin expression by inhibiting translation.

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$42.00
$214.00
$832.00
$66.00
394
(16)

Puromycin induces premature termination of protein synthesis, impacting translation and lowering κ-Actin levels.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$97.00
$328.00
$676.00
$1467.00
6
(1)

Rifampicin inhibits bacterial RNA polymerase, indirectly suppressing κ-Actin expression by interfering with transcription.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$99.00
$259.00
36
(2)

Anisomycin hinders protein synthesis by blocking peptidyl transferase activity, leading to reduced κ-Actin synthesis.

Cordycepin

73-03-0sc-203902
10 mg
$101.00
5
(1)

Cordycepin interferes with mRNA synthesis, impacting transcription and contributing to the downregulation of κ-Actin.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$69.00
$266.00
8
(1)

Mycophenolic acid inhibits inosine monophosphate dehydrogenase, indirectly affecting κ-Actin expression by disrupting purine synthesis.

Blasticidin S Hydrochloride

3513-03-9sc-204655A
sc-204655
25 mg
100 mg
$367.00
$520.00
20
(2)

Blasticidin S induces premature termination during translation, inhibiting protein synthesis and reducing κ-Actin levels.

Ellipticine

519-23-3sc-200878
sc-200878A
10 mg
50 mg
$145.00
$569.00
4
(1)

Ellipticine intercalates into DNA, disrupting DNA structure and inhibiting transcription, leading to decreased κ-Actin mRNA.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$37.00
$152.00
11
(1)

5-Fluorouracil interferes with RNA synthesis, affecting the expression of κ-Actin by disrupting the production of mRNA.