Date published: 2025-12-6

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IP3R Antibodies

Santa Cruz Biotechnology features a diverse variety of IP3R monoclonal antibodies for advanced research in cellular signaling pathways. IP3R Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Inositol trisphosphate receptors (IP3Rs) play a crucial role in calcium signaling by mediating the release of calcium ions from the endoplasmic reticulum in response to inositol trisphosphate. This calcium release is essential for numerous cellular processes, including muscle contraction, neurotransmitter release, and cell proliferation. Understanding IP3Rs is vital for elucidating their involvement in various physiological and pathological conditions, including cardiac function and neurodegenerative diseases. IP3R monoclonal antibodies enable researchers to investigate calcium signaling mechanisms across multiple experimental approaches. Studying IP3Rs contributes significantly to understanding cellular communication and regulation. Research utilizing IP3R monoclonal antibodies helps advance knowledge of disease mechanisms and potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of cellular signaling pathways and their impact on human health.

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IP3R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IP3R-I Antibody (E-8)

sc-271197mouse IgG1 κ1894-1973 (h)WB, IP, IF, IHC(P), ELISAm, r, h
24
(9)

IP3R-I/II/III Antibody (B-2)

sc-377518mouse IgG2b2402-2701 (h)WB, IP, IF, IHC(P), ELISAm, r, h
26
(13)

IP3R-II Antibody (A-5)

sc-398434mouse IgG2b κ2666-2695 (h)WB, IP, IF, ELISAm, r, h
25
(11)

IP3R CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IP3R-I CRISPR/Cas9 KO Plasmid (h)

sc-400986hGene KnockoutGFP0
(0)

IP3R-I CRISPR/Cas9 KO Plasmid (h2)

sc-400986-KO-2hGene KnockoutGFP0
(0)

IP3R-I HDR Plasmid (h2)

sc-400986-HDR-2hHomology Directed RepairPuromycin0
(0)

IP3R-I Double Nickase Plasmid (h)

sc-400986-NIChGene KnockoutPuromycin0
(0)

IP3R-I Double Nickase Plasmid (h2)

sc-400986-NIC-2hGene KnockoutPuromycin0
(0)

IP3R-I CRISPR/Cas9 KO Plasmid (m)

sc-421192mGene KnockoutGFP
1
(0)

IP3R-I HDR Plasmid (m)

sc-421192-HDRmHomology Directed RepairPuromycin
1
(0)

IP3R-I Double Nickase Plasmid (m)

sc-421192-NICmGene KnockoutPuromycin
1
(0)

IP3R-I Double Nickase Plasmid (m2)

sc-421192-NIC-2mGene KnockoutPuromycin
1
(0)

IP3R-II CRISPR/Cas9 KO Plasmid (h2)

sc-401067-KO-2hGene KnockoutGFP0
(0)

IP3R-II HDR Plasmid (h2)

sc-401067-HDR-2hHomology Directed RepairPuromycin0
(0)

IP3R-II Double Nickase Plasmid (h)

sc-401067-NIChGene KnockoutPuromycin0
(0)

IP3R-II Double Nickase Plasmid (h2)

sc-401067-NIC-2hGene KnockoutPuromycin0
(0)

IP3R-II CRISPR/Cas9 KO Plasmid (m)

sc-421193mGene KnockoutGFP0
(0)

IP3R-II HDR Plasmid (m)

sc-421193-HDRmHomology Directed RepairPuromycin0
(0)

IP3R-II Double Nickase Plasmid (m)

sc-421193-NICmGene KnockoutPuromycin0
(0)

IP3R-II Double Nickase Plasmid (m2)

sc-421193-NIC-2mGene KnockoutPuromycin0
(0)

IP3R-III CRISPR/Cas9 KO Plasmid (h)

sc-402138hGene KnockoutGFP
1
(0)

IP3R-III HDR Plasmid (h)

sc-402138-HDRhHomology Directed RepairPuromycin
1
(0)

IP3R-III Double Nickase Plasmid (h)

sc-402138-NIChGene KnockoutPuromycin
1
(0)

IP3R-III Double Nickase Plasmid (h2)

sc-402138-NIC-2hGene KnockoutPuromycin
1
(0)

IP3R-III CRISPR/Cas9 KO Plasmid (m)

sc-421194mGene KnockoutGFP
1
(0)

IP3R-III HDR Plasmid (m)

sc-421194-HDRmHomology Directed RepairPuromycin
1
(0)

IP3R-III Double Nickase Plasmid (m)

sc-421194-NICmGene KnockoutPuromycin
1
(0)

IP3R-III Double Nickase Plasmid (m2)

sc-421194-NIC-2mGene KnockoutPuromycin
1
(0)

IP3R CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IP3R-I CRISPR Activation Plasmid (h)

sc-400986-ACThGene ActivationPuro, Blast, Hygro0
(0)

IP3R-I CRISPR Activation Plasmid (h2)

sc-400986-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IP3R-I Lentiviral Activation Particles (h)

sc-400986-LAChGene ActivationPuro, Blast, Hygro0
(0)

IP3R-I Lentiviral Activation Particles (h2)

sc-400986-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IP3R-I CRISPR Activation Plasmid (m)

sc-421192-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-I CRISPR Activation Plasmid (m2)

sc-421192-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-I Lentiviral Activation Particles (m)

sc-421192-LACmGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-I Lentiviral Activation Particles (m2)

sc-421192-LAC-2mGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-II CRISPR Activation Plasmid (h)

sc-401067-ACThGene ActivationPuro, Blast, Hygro0
(0)

IP3R-II CRISPR Activation Plasmid (h2)

sc-401067-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IP3R-II Lentiviral Activation Particles (h)

sc-401067-LAChGene ActivationPuro, Blast, Hygro0
(0)

IP3R-II Lentiviral Activation Particles (h2)

sc-401067-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IP3R-II CRISPR Activation Plasmid (m)

sc-421193-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IP3R-II CRISPR Activation Plasmid (m2)

sc-421193-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

IP3R-II Lentiviral Activation Particles (m)

sc-421193-LACmGene ActivationPuro, Blast, Hygro0
(0)

IP3R-II Lentiviral Activation Particles (m2)

sc-421193-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

IP3R-III CRISPR Activation Plasmid (h)

sc-402138-ACThGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-III CRISPR Activation Plasmid (h2)

sc-402138-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-III Lentiviral Activation Particles (h)

sc-402138-LAChGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-III Lentiviral Activation Particles (h2)

sc-402138-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-III CRISPR Activation Plasmid (m)

sc-421194-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-III CRISPR Activation Plasmid (m2)

sc-421194-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-III Lentiviral Activation Particles (m)

sc-421194-LACmGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-III Lentiviral Activation Particles (m2)

sc-421194-LAC-2mGene ActivationPuro, Blast, Hygro
1
(0)

IP3R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IP3R-I siRNA (h)

sc-42475hGene SilencingN/A
6
(1)

IP3R-I shRNA Plasmid (h)

sc-42475-SHhGene SilencingPuromycin
6
(1)

IP3R-I shRNA (h) Lentiviral Particles

sc-42475-VhGene SilencingPuromycin
6
(1)

IP3R-I siRNA (m)

sc-42476mGene SilencingN/A
3
(0)

IP3R-I shRNA Plasmid (m)

sc-42476-SHmGene SilencingPuromycin
3
(0)

IP3R-I shRNA (m) Lentiviral Particles

sc-42476-VmGene SilencingPuromycin
3
(0)

IP3R-II siRNA (h)

sc-35698hGene SilencingN/A
2
(0)

IP3R-II shRNA Plasmid (h)

sc-35698-SHhGene SilencingPuromycin
2
(0)

IP3R-II shRNA (h) Lentiviral Particles

sc-35698-VhGene SilencingPuromycin
2
(0)

IP3R-II siRNA (m)

sc-35699mGene SilencingN/A0
(0)

IP3R-II shRNA Plasmid (m)

sc-35699-SHmGene SilencingPuromycin0
(0)

IP3R-II shRNA (m) Lentiviral Particles

sc-35699-VmGene SilencingPuromycin0
(0)

IP3R-III siRNA (h)

sc-42477hGene SilencingN/A
1
(0)

IP3R-III shRNA Plasmid (h)

sc-42477-SHhGene SilencingPuromycin
1
(0)

IP3R-III shRNA (h) Lentiviral Particles

sc-42477-VhGene SilencingPuromycin
1
(0)

IP3R-III siRNA (m)

sc-42478mGene SilencingN/A0
(0)

IP3R-III shRNA Plasmid (m)

sc-42478-SHmGene SilencingPuromycin0
(0)

IP3R-III shRNA (m) Lentiviral Particles

sc-42478-VmGene SilencingPuromycin0
(0)