Date published: 2025-11-24

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IP3R-I Antibodies

Santa Cruz Biotechnology delivers a wide array of IP3R-I monoclonal antibodies for the specific detection and analysis of inositol 1,4,5-trisphosphate receptor type I. IP3R-I monoclonal antibodies are validated for multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The inositol 1,4,5-trisphosphate receptor type I plays a central role in calcium signaling pathways, mediating the release of calcium ions from the endoplasmic reticulum in response to cellular stimuli. IP3R-I is essential for various physiological processes, including muscle contraction, neurotransmitter release, and cell proliferation. Understanding the function and regulation of IP3R-I contributes significantly to research in cellular functions and disease states. Researchers worldwide rely on IP3R-I monoclonal antibodies to advance their studies in calcium signaling mechanisms. IP3R-I monoclonal antibodies enable precise detection and characterization of signaling pathways across diverse experimental conditions. The exceptional specificity of IP3R-I monoclonal antibodies from Santa Cruz Biotechnology continues to support breakthrough discoveries in calcium signaling research and cellular biology.

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IP3R-I Antibodies

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IP3R-I Antibody (E-8)

sc-271197mouse IgG1 κ1894-1973 (h)WB, IP, IF, IHC(P), ELISAm, r, h
24
(9)

IP3R-I/II/III Antibody (B-2)

sc-377518mouse IgG2b2402-2701 (h)WB, IP, IF, IHC(P), ELISAm, r, h
26
(13)

IP3R-I CRISPR Knockout, HDR and Double Nickase Plasmids

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IP3R-I CRISPR/Cas9 KO Plasmid (h)

sc-400986hGene KnockoutGFP0
(0)

IP3R-I CRISPR/Cas9 KO Plasmid (h2)

sc-400986-KO-2hGene KnockoutGFP0
(0)

IP3R-I HDR Plasmid (h2)

sc-400986-HDR-2hHomology Directed RepairPuromycin0
(0)

IP3R-I Double Nickase Plasmid (h)

sc-400986-NIChGene KnockoutPuromycin0
(0)

IP3R-I Double Nickase Plasmid (h2)

sc-400986-NIC-2hGene KnockoutPuromycin0
(0)

IP3R-I CRISPR/Cas9 KO Plasmid (m)

sc-421192mGene KnockoutGFP
1
(0)

IP3R-I HDR Plasmid (m)

sc-421192-HDRmHomology Directed RepairPuromycin
1
(0)

IP3R-I Double Nickase Plasmid (m)

sc-421192-NICmGene KnockoutPuromycin
1
(0)

IP3R-I Double Nickase Plasmid (m2)

sc-421192-NIC-2mGene KnockoutPuromycin
1
(0)

IP3R-I CRISPR Activation Products

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IP3R-I CRISPR Activation Plasmid (h)

sc-400986-ACThGene ActivationPuro, Blast, Hygro0
(0)

IP3R-I CRISPR Activation Plasmid (h2)

sc-400986-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IP3R-I Lentiviral Activation Particles (h)

sc-400986-LAChGene ActivationPuro, Blast, Hygro0
(0)

IP3R-I Lentiviral Activation Particles (h2)

sc-400986-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IP3R-I CRISPR Activation Plasmid (m)

sc-421192-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-I CRISPR Activation Plasmid (m2)

sc-421192-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-I Lentiviral Activation Particles (m)

sc-421192-LACmGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-I Lentiviral Activation Particles (m2)

sc-421192-LAC-2mGene ActivationPuro, Blast, Hygro
1
(0)

IP3R-I siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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IP3R-I siRNA (h)

sc-42475hGene SilencingN/A
6
(1)

IP3R-I shRNA Plasmid (h)

sc-42475-SHhGene SilencingPuromycin
6
(1)

IP3R-I shRNA (h) Lentiviral Particles

sc-42475-VhGene SilencingPuromycin
6
(1)

IP3R-I siRNA (m)

sc-42476mGene SilencingN/A
3
(0)

IP3R-I shRNA Plasmid (m)

sc-42476-SHmGene SilencingPuromycin
3
(0)

IP3R-I shRNA (m) Lentiviral Particles

sc-42476-VmGene SilencingPuromycin
3
(0)