The chemical class of IMPDH2 activators consists of a diverse range of compounds that can potentially influence the activity of IMPDH2 indirectly through their effects on metabolic pathways, energy metabolism, and nucleotide biosynthesis. These compounds, while not directly targeting IMPDH2, can modulate the cellular environment and pathways that regulate IMPDH2 function and its associated processes. Compounds such as Metformin, Berberine, Resveratrol, and EGCG impact key metabolic pathways within cells, crucial for the regulation of nucleotide synthesis processes in which IMPDH2 is involved. Metformin, by influencing cellular energy states, and Berberine, through its modulation of metabolic pathways, can induce changes in cellular processes that potentially affect IMPDH2 activity in guanine nucleotide production.
Furthermore, compounds like Forskolin, Curcumin, Sulforaphane, Quercetin, N-Acetylcysteine, Caffeine, Ginsenoside, and Alpha-Lipoic Acid, known for their diverse effects on cellular metabolism, antioxidant properties, and energy regulation, can also indirectly influence IMPDH2 activity. By modulating pathways related to energy metabolism, oxidative stress, and nucleotide biosynthesis, these compounds can impact the function of IMPDH2 in maintaining nucleotide pool balance and cellular metabolic homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
An antidiabetic drug that influences metabolic pathways, potentially affecting IMPDH2 by modulating cellular energy states and nucleotide synthesis. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Known to modulate metabolic pathways, potentially influencing IMPDH2 activity through its effects on cellular metabolism and nucleotide biosynthesis. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Modulates metabolic pathways, potentially affecting IMPDH2 activity in nucleotide synthesis and energy metabolism. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Influences cellular signaling and metabolism, potentially impacting IMPDH2 activity in the purine nucleotide synthesis pathway. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases cAMP levels, potentially affecting IMPDH2 by altering signaling pathways that regulate metabolic processes and nucleotide synthesis. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Affects various signaling pathways, potentially modulating IMPDH2 activity in metabolic and nucleotide synthesis pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Influences cellular stress responses, potentially modulating IMPDH2 activity through pathways related to cellular metabolism. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Acts as an antioxidant, potentially impacting IMPDH2 activity in processes related to cellular metabolism and nucleotide synthesis. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
Known for its role in redox balance, potentially influencing IMPDH2 activity by modulating metabolic pathways. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Influences various cellular processes, potentially impacting IMPDH2 activity in metabolic pathways and nucleotide biosynthesis. | ||||||