Date published: 2026-4-1

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IMPDH2 Activators

The chemical class of IMPDH2 activators consists of a diverse range of compounds that can potentially influence the activity of IMPDH2 indirectly through their effects on metabolic pathways, energy metabolism, and nucleotide biosynthesis. These compounds, while not directly targeting IMPDH2, can modulate the cellular environment and pathways that regulate IMPDH2 function and its associated processes. Compounds such as Metformin, Berberine, Resveratrol, and EGCG impact key metabolic pathways within cells, crucial for the regulation of nucleotide synthesis processes in which IMPDH2 is involved. Metformin, by influencing cellular energy states, and Berberine, through its modulation of metabolic pathways, can induce changes in cellular processes that potentially affect IMPDH2 activity in guanine nucleotide production.

Furthermore, compounds like Forskolin, Curcumin, Sulforaphane, Quercetin, N-Acetylcysteine, Caffeine, Ginsenoside, and Alpha-Lipoic Acid, known for their diverse effects on cellular metabolism, antioxidant properties, and energy regulation, can also indirectly influence IMPDH2 activity. By modulating pathways related to energy metabolism, oxidative stress, and nucleotide biosynthesis, these compounds can impact the function of IMPDH2 in maintaining nucleotide pool balance and cellular metabolic homeostasis.

SEE ALSO...

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

An antidiabetic drug that influences metabolic pathways, potentially affecting IMPDH2 by modulating cellular energy states and nucleotide synthesis.

Berberine

2086-83-1sc-507337
250 mg
$92.00
1
(0)

Known to modulate metabolic pathways, potentially influencing IMPDH2 activity through its effects on cellular metabolism and nucleotide biosynthesis.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Modulates metabolic pathways, potentially affecting IMPDH2 activity in nucleotide synthesis and energy metabolism.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

Influences cellular signaling and metabolism, potentially impacting IMPDH2 activity in the purine nucleotide synthesis pathway.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Increases cAMP levels, potentially affecting IMPDH2 by altering signaling pathways that regulate metabolic processes and nucleotide synthesis.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Affects various signaling pathways, potentially modulating IMPDH2 activity in metabolic and nucleotide synthesis pathways.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Influences cellular stress responses, potentially modulating IMPDH2 activity through pathways related to cellular metabolism.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Acts as an antioxidant, potentially impacting IMPDH2 activity in processes related to cellular metabolism and nucleotide synthesis.

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$34.00
$74.00
$270.00
$114.00
34
(1)

Known for its role in redox balance, potentially influencing IMPDH2 activity by modulating metabolic pathways.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Influences various cellular processes, potentially impacting IMPDH2 activity in metabolic pathways and nucleotide biosynthesis.