IL-4Rα Activators
IL-4Rα (Interleukin-4 receptor alpha) activators belong to a class of molecules that play a pivotal role in modulating the immune system and inflammatory responses in the body. IL-4Rα is a receptor protein found on the surface of certain immune cells, including B cells, T cells, and macrophages. When activated, it initiates a cascade of signaling events that regulate immune cell differentiation, proliferation, and function. IL-4Rα activators are compounds or substances that interact with IL-4Rα, typically by binding to it, and trigger the receptor's downstream signaling pathways.
The activation of IL-4Rα by its ligands, such as interleukin-4 (IL-4) and interleukin-13 (IL-13), is a crucial aspect of the immune response. It can lead to the production of specific cytokines, cell differentiation, and immune cell activation. IL-4Rα activators can mimic the effects of these natural ligands or modulate the receptor's activity, thereby influencing the immune system's response to various stimuli.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a derivative of vitamin A, is involved in regulating immune responses and cell differentiation. It has been shown to influence the expression of various cytokine receptors, potentially including IL-4Rα, though the exact mechanisms remain to be fully elucidated. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
This active form of vitamin D plays a vital role in immune regulation. It can modulate the expression of various genes related to immune responses, and may have the potential to induce IL-4Rα expression in certain immune cells. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane, found in cruciferous vegetables, is known for its antioxidative and anti-inflammatory properties. It may influence the expression of various proteins related to immune responses, potentially including IL-4Rα. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, the active compound in turmeric, has anti-inflammatory and antioxidant properties. It has been shown to modulate the expression of various proteins and genes related to immune responses, and may play a role in inducing IL-4Rα expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, found in grapes and red wine, has antioxidant and anti-inflammatory properties. It may influence the expression of proteins related to immune responses, potentially including IL-4Rα. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is a flavonoid with anti-inflammatory and antioxidant properties. It has been shown to modulate the expression of various proteins related to immune responses, and may have a role in inducing IL-4Rα expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a major component of green tea, has anti-inflammatory and antioxidative properties. It may influence the expression of proteins related to immune responses, potentially including IL-4Rα. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is an essential mineral with various roles in immune function and cell signaling. It may influence the expression of various cytokine receptors, potentially including IL-4Rα, though the mechanisms are complex and not fully understood. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $61.00 | 1 | |
Selenium is an essential trace element with roles in antioxidant defense and immune function. It may influence the expression of various proteins related to immune responses, potentially including IL-4Rα. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic acid, found in certain fruits and nuts, has antioxidant and anti-inflammatory properties. It may modulate the expression of various proteins related to immune responses, and could potentially influence IL-4Rα expression. | ||||||