IFI-27 Activators
IFI-27 Activators are primarily composed of DNA methyltransferase inhibitors, histone deacetylase inhibitors, and bromodomain inhibitors. The DNA methyltransferase inhibitors, such as 5-Azacytidine and Decitabine, function by reducing DNA methylation levels, potentially leading to the demethylation of the IFI-27 gene promoter. This demethylation can enhance the gene expression of IFI-27, leading to increased functional activity of the protein.
Histone deacetylase inhibitors, including Vorinostat, Entinostat, Romidepsin, and Trichostatin A, promote the acetylation of histones. This acetylation leads to a more relaxed chromatin state and enhanced gene expression. This process can enhance IFI-27 functional activity by promoting its gene expression. Bromodomain inhibitors such as JQ1, I-BET151, GSK525762, I-BET762, PFI-1, and CPI-0610 disrupt the binding of bromodomain proteins to acetylated histones. This disruption can lead to changes in gene expression, potentially enhancing the functional activity of IFI-27. These diverse compounds offer various means to enhance the functional activity of IFI-27, demonstrating the interconnectivity of cellular signaling networks and the potential influence these activators can exert on the functionality of IFI-27.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor that can reduce DNA methylation levels and consequently alter gene expression. Its action can lead to the demethylation of the IFI-27 gene promoter, enhancing IFI-27 functional activity. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Decitabine is another DNA methyltransferase inhibitor. It can also reduce DNA methylation levels, leading to the potential demethylation of the IFI-27 gene promoter and enhanced IFI-27 functional activity. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat is a histone deacetylase inhibitor. It promotes the acetylation of histones, leading to a more relaxed chromatin state and enhanced gene expression. This process can lead to increased IFI-27 functional activity. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Entinostat is another histone deacetylase inhibitor. Its action can lead to a more relaxed chromatin state and enhanced gene expression, including that of IFI-27. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $214.00 $622.00 | 1 | |
Romidepsin is a potent histone deacetylase inhibitor. It promotes the acetylation of histones, leading to a more relaxed chromatin state and enhanced gene expression, including that of IFI-27. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor. Its action can lead to a more relaxed chromatin state and enhanced gene expression, including that of IFI-27. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 is a bromodomain inhibitor that can disrupt the binding of bromodomain proteins to acetylated histones. This disruption can lead to changes in gene expression, potentially enhancing IFI-27 functional activity. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
I-BET151 is another bromodomain inhibitor. Its action can disrupt the binding of bromodomain proteins to acetylated histones, potentially enhancing IFI-27 functional activity. | ||||||
GSK 525762A | 1260907-17-2 | sc-490339 sc-490339A sc-490339B sc-490339C sc-490339D | 5 mg 10 mg 50 mg 100 mg 1 g | $300.00 $540.00 $940.00 $1680.00 $5900.00 | ||
GSK525762 is a bromodomain inhibitor. Its action can disrupt the binding of bromodomain proteins to acetylated histones, potentially enhancing IFI-27 functional activity. | ||||||
PFI-1 | 1403764-72-6 | sc-478504 | 5 mg | $96.00 | ||
PFI-1 is a bromodomain inhibitor. Its action can disrupt the binding of bromodomain proteins to acetylated histones, potentially enhancing IFI-27 functional activity. | ||||||