Id3 Inhibitors
Common Id3 Inhibitors include, but are not limited to Retinoic Acid, all trans CAS 302-79-4, 5-Aza-2′-Deoxycytidine CAS 2353-33-5, Trichostatin A CAS 58880-19-6, Dexamethasone CAS 50-02-2 and PD 98059 CAS 167869-21-8.
Inhibitor of DNA binding 3 (Id3) is a member of the helix-loop-helix (HLH) family of transcriptional regulatory proteins. These proteins play crucial roles in cell differentiation, proliferation, and apoptosis. Id3, in particular, is known to lack a DNA-binding domain and hence does not directly bind to DNA. Instead, it exerts its influence by binding to other transcription factors, often inhibiting their function. By doing so, Id3 serves as a regulator of the transcriptional activity of its binding partners, modulating the expression of downstream genes and influencing various cellular processes. Given its central role in these pathways, the precise regulation of Id3 activity is essential for maintaining cellular homeostasis.
Id3 inhibitors are chemical compounds specifically designed to reduce or inhibit the activity of the Id3 protein. These inhibitors operate by disrupting the protein's interaction with its binding partners or by preventing its proper folding and stability. Such disruption can lead to a cascade of effects on downstream pathways, given Id3's role as a regulatory node in various signaling networks.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
This DNA methyltransferase inhibitor might affect Id3 expression by altering the methylation status of the Id3 gene. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A, an HDAC inhibitor, can modulate transcription factor activities, possibly leading to reduced Id3 expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a glucocorticoid, may reduce Id3 expression by affecting glucocorticoid-responsive signaling pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a MEK inhibitor that might suppress certain pathways, potentially leading to reduced Id3 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that might affect several downstream pathways, potentially decreasing Id3 expression. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin, another PI3K inhibitor, can modulate Id3 expression by affecting PI3K-AKT signaling. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor. It might reduce Id3 expression by modulating JNK signaling pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a Rho-associated kinase inhibitor, which might reduce Id3 expression by affecting Rho signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAPK, which may affect Id3 expression by modulating the MAPK signaling pathway. | ||||||