Date published: 2025-9-25

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HSP 70 Antibodies

Santa Cruz Biotechnology offers a broad range of HSP 70 monoclonal antibodies for research in cellular stress responses and protein homeostasis. HSP 70 monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HSP 70, or Heat Shock Protein 70, plays a critical role in protecting cells from stress by facilitating protein folding, preventing aggregation, and assisting in the degradation of misfolded proteins. Its expression increases in response to stressors such as heat, toxins, and oxidative stress, making it a key player in cellular survival and function. Understanding the dynamics of HSP 70 is essential for elucidating mechanisms of disease and developing therapeutic strategies. HSP 70 research has revealed significant insights into cellular stress responses and protein quality control mechanisms. Researchers have identified multiple functions of HSP 70 in maintaining cellular health, from protein transport to preventing apoptosis. Current studies focus on understanding HSP 70's role in neurodegenerative diseases, cancer, and aging. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of HSP 70's role in health and disease.

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HSP 70 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HSP70 Antibody (3A3)

sc-32239mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
206
(29)

HSP70 Antibody (F-3)

sc-373867mouse IgG2b κ565-601 (h)WB, IP, IF, IHC(P), ELISAm, r, h
20
(9)

HSP70 Antibody (C92F3A-5)

sc-66048mouse IgG1436-503 (h)WB, IP, IF, IHC(P), FCMm, r, h, bovine, porcine, canine, Drosophila and C. elegans
121
(12)

HSP70 Antibody (N27F3-4)

sc-66049mouse IgG1403-640 (h)WB, IP, IF, IHC(P), FCMbroad mammalian species
14
(7)

HSP70 Antibody (4E7)

sc-69705mouse IgG11-641 (h)WB, IPh
10
(4)

HSP70 Antibody (4G4)

sc-59569mouse IgG2b κ(h)WB, IP, IF, IHC(P)m, r, h
17
(2)

HSP70 Antibody (6D444)

sc-71278mouse IgG2b κ(h)WB, IPm, r, h
1
(2)

HSC70/HSP70 Antibody (W27)

sc-24mouse IgG2a λ(h)WB, IP, IF, IHC(P), FCMm, r, h
522
(40)

HSC70/HSP70 Antibody (BRM-22)

sc-59572mouse IgG1FL (bovine)WB, IP, IF, ELISAm, r, h, Drosophila and C. elegans
19
(5)

HSC70/HSP70 Antibody (H-2)

sc-137211mouse IgG2a κ342-641 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(2)

HSC70/HSP70 Antibody (2A4)

sc-59570mouse IgM κ(h)WB, IP, IF, IHC(P)m, r, h
8
(4)

HSC70/HSP70 Antibody (5A5)

sc-59571mouse IgG2b κ(h)WB, IP, IF, IHC(P)m, r, h
4
(3)

HSC70/HSP70 Antibody (B-12)

sc-137239mouse IgG2a λ342-641 (h)WB, IP, IF, ELISAm, r, h
6
(1)

HSC70/HSP70 Antibody (G-1)

sc-137210mouse IgG2a κ342-641 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(3)

HSP 70 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSP70-1 CRISPR/Cas9 KO Plasmid (h)

sc-418088hGene KnockoutGFP
1
(0)

HSP70-1 HDR Plasmid (h)

sc-418088-HDRhHomology Directed RepairPuromycin
1
(0)

HSP70-1 Double Nickase Plasmid (h)

sc-418088-NIChGene KnockoutPuromycin
1
(0)

HSP70-1 Double Nickase Plasmid (h2)

sc-418088-NIC-2hGene KnockoutPuromycin
1
(0)

HSP70-1 CRISPR/Cas9 KO Plasmid (m2)

sc-420978-KO-2mGene KnockoutGFP0
(0)

HSP70-1 Double Nickase Plasmid (m)

sc-420978-NICmGene KnockoutPuromycin0
(0)

HSP70-1 Double Nickase Plasmid (m2)

sc-420978-NIC-2mGene KnockoutPuromycin0
(0)

HSP70-2 CRISPR/Cas9 KO Plasmid (h)

sc-417733hGene KnockoutGFP0
(0)

HSP70-2 HDR Plasmid (h)

sc-417733-HDRhHomology Directed RepairPuromycin0
(0)

HSP70-2 Double Nickase Plasmid (h)

sc-417733-NIChGene KnockoutPuromycin0
(0)

HSP70-2 Double Nickase Plasmid (h2)

sc-417733-NIC-2hGene KnockoutPuromycin0
(0)

Hsp70-3 CRISPR/Cas9 KO Plasmid (m)

sc-431448mGene KnockoutGFP0
(0)

Hsp70-3 HDR Plasmid (m)

sc-431448-HDRmHomology Directed RepairPuromycin0
(0)

Hsp70-3 Double Nickase Plasmid (m)

sc-431448-NICmGene KnockoutPuromycin0
(0)

Hsp70-3 Double Nickase Plasmid (m2)

sc-431448-NIC-2mGene KnockoutPuromycin0
(0)

HSP 70 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSP70-1 CRISPR Activation Plasmid (h)

sc-418088-ACThGene ActivationPuro, Blast, Hygro
1
(0)

HSP70-2 CRISPR Activation Plasmid (h)

sc-417733-ACThGene ActivationPuro, Blast, Hygro0
(0)

HSP70-1 CRISPR Activation Plasmid (h2)

sc-418088-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

HSP70-1 Lentiviral Activation Particles (h)

sc-418088-LAChGene ActivationPuro, Blast, Hygro
1
(0)

HSP70-1 Lentiviral Activation Particles (h2)

sc-418088-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

HSP70-1 CRISPR Activation Plasmid (m)

sc-420978-ACTmGene ActivationPuro, Blast, Hygro0
(0)

HSP70-1 CRISPR Activation Plasmid (m2)

sc-420978-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

HSP70-1 Lentiviral Activation Particles (m)

sc-420978-LACmGene ActivationPuro, Blast, Hygro0
(0)

HSP70-1 Lentiviral Activation Particles (m2)

sc-420978-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

HSP70-2 CRISPR Activation Plasmid (h2)

sc-417733-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

HSP70-2 Lentiviral Activation Particles (h)

sc-417733-LAChGene ActivationPuro, Blast, Hygro0
(0)

HSP70-2 Lentiviral Activation Particles (h2)

sc-417733-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Hsp70-3 CRISPR Activation Plasmid (m)

sc-431448-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Hsp70-3 CRISPR Activation Plasmid (m2)

sc-431448-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Hsp70-3 Lentiviral Activation Particles (m)

sc-431448-LACmGene ActivationPuro, Blast, Hygro0
(0)

Hsp70-3 Lentiviral Activation Particles (m2)

sc-431448-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

HSP 70 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSP70 siRNA (h)

sc-29352hGene SilencingN/A
42
(2)

HSP70 siRNA (h2)

sc-44196hGene SilencingN/A0
(0)

HSP70 shRNA Plasmid (h)

sc-29352-SHhGene SilencingPuromycin
42
(2)

HSP70 shRNA Plasmid (h2)

sc-44196-SHhGene SilencingPuromycin0
(0)

HSP70 shRNA (h) Lentiviral Particles

sc-29352-VhGene SilencingPuromycin
42
(2)

HSP70 shRNA (h2) Lentiviral Particles

sc-44196-VhGene SilencingPuromycin0
(0)

HSP70 siRNA (m)

sc-35605mGene SilencingN/A
2
(0)

HSP70 shRNA Plasmid (m)

sc-35605-SHmGene SilencingPuromycin
2
(0)

HSP70 shRNA (m) Lentiviral Particles

sc-35605-VmGene SilencingPuromycin
2
(0)

HSP70 siRNA (r)

sc-270278rGene SilencingN/A
3
(0)

HSP70 shRNA Plasmid (r)

sc-270278-SHrGene SilencingPuromycin
3
(0)

HSP70 shRNA (r) Lentiviral Particles

sc-270278-VrGene SilencingPuromycin
3
(0)

HSP70 siRNA (S. scrofa)

sc-77336S. scrofaGene SilencingN/A0
(0)

HSP70 shRNA Plasmid (S. scrofa)

sc-77336-SHS. scrofaGene SilencingPuromycin0
(0)

HSP70 shRNA (S. scrofa) Lentiviral Particles

sc-77336-VS. scrofaGene SilencingPuromycin0
(0)

HSP70-1 siRNA (m)

sc-108044mGene SilencingN/A0
(0)

HSP70-1 shRNA Plasmid (m)

sc-108044-SHmGene SilencingPuromycin0
(0)

HSP70-1 shRNA (m) Lentiviral Particles

sc-108044-VmGene SilencingPuromycin0
(0)

HSP70-2 siRNA (h)

sc-105545hGene SilencingN/A0
(0)

HSP70-2 shRNA Plasmid (h)

sc-105545-SHhGene SilencingPuromycin0
(0)

HSP70-2 shRNA (h) Lentiviral Particles

sc-105545-VhGene SilencingPuromycin0
(0)