HSP70 Antibody (4E7): sc-69705
- HSP70 Antibody (4E7) is a mouse monoclonal IgG1, cited in 10 publications, provided at 50 µg/500 µl
- raised against a recombinant protein corresponding to amino acids 1-641 of HSP 70 of human origin
- recommended for detection of HSP 70 of human origin by WB and IP
- See HSC70/HSP70 (W27): sc-24 for HSP70 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HSP70 Antibody (4E7). This work is in progress.
HSP 70 Antibody (4E7) is a mouse monoclonal IgG1 antibody that detects HSP 70 in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). HSP 70 is a crucial member of the heat shock protein family, which plays a vital role in cellular stress responses, particularly in protecting cells from damage caused by heat and other stressors. HSP 70 functions primarily as a molecular chaperone, facilitating the proper folding of nascent polypeptide chains and preventing the aggregation of misfolded proteins, which is essential for maintaining cellular homeostasis. HSP 70 is predominantly located in the cytosol and nucleus of mammalian cells, where HSP 70 assists in the translocation of proteins across cellular membranes and into organelles, thereby ensuring that proteins reach their correct destinations and maintain their functional conformations. HSP 70′s ability to respond to stress by increasing expression levels is critical for cell survival, especially under conditions that may lead to protein denaturation. Anti-HSP 70 antibody (4E7) enables researchers to effectively study the expression and function of HSP 70, contributing to a deeper understanding of HSP 70′s role in cellular stress responses and potential implications in diseases associated with protein misfolding.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSP70 Antibody (4E7) | sc-69705 | 50 µg/500 µl | $322.00 |