HSC70/HSP70 Antibody (2A4): sc-59570
- HSC70/HSP70 Antibody (2A4) is a mouse monoclonal IgM κ, cited in 8 publications, provided at 200 µg/ml
- raised against recombinant HSP 70/HSC 70 of human origin
- recommended for detection of several members of the heat shock protein 70 kDa (HSP 70) gene family including HSP 70, HSC 70 and, following heat shock, HSP 72 of mouse, rat, human and Drosophila origin by WB, IP, IF and IHC(P)
- See HSC70/HSP70 (W27): sc-24 for HSC70/HSP70 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for HSC70/HSP70 Antibody (2A4) for WB and IHC(P) applications. This reagent is now offered in a bundle with HSC70/HSP70 Antibody (2A4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
HSP 70/HSC 70 Antibody (2A4) is a mouse monoclonal IgM antibody that detects HSP 70/HSC 70 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. HSP 70/HSC 70 are crucial members of the heat shock protein family, known for their role as molecular chaperones that assist in the proper folding of nascent polypeptide chains and the assembly of multi-protein complexes. HSP 70/HSC 70 are vital for cellular homeostasis, particularly under stress conditions, as these proteins help prevent the accumulation of misfolded proteins that can lead to cellular dysfunction and disease. HSP 70 is strongly induced in response to heat stress, highlighting HSP 70′s importance in protecting cells from thermal damage. HSP 70/HSC 70 interaction with various client proteins, including those involved in apoptosis and cell signaling, underscores their significance in maintaining cellular integrity and function. HSP 70′s ability to facilitate polypeptide translocation across cellular membranes and into the nucleus further emphasizes HSP 70′s essential role in cellular processes. With broad species reactivity and versatility in various applications, anti-HSP 70/HSC 70 antibody (2A4) serves as an invaluable tool for researchers studying stress responses and protein homeostasis in mammalian cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSC70/HSP70 Antibody (2A4) | sc-59570 | 200 µg/ml | $316.00 | |||
HSC70/HSP70 Antibody (2A4): m-IgGκ BP-HRP Bundle | sc-551946 | 200 µg Ab; 40 µg BP | $354.00 |