HSP70 Antibody (C92F3A-5): sc-66048

HSP 70 Antibody (C92F3A-5) is a mouse monoclonal IgG1 antibody that detects HSP 70 across various species including mouse, rat, human, bovine, porcine, canine, Drosophila, and C. elegans, and is suitable for applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and flow cytometry (FCM). Anti-HSP 70 antibody (C92F3A-5) is available in a non-conjugated form and targets a member of the highly conserved HSP 70 family, which plays a crucial role in cellular stress responses. HSP 70 functions primarily as a molecular chaperone, assisting in the proper folding of nascent polypeptide chains and preventing the aggregation of misfolded proteins, which is vital for maintaining cellular homeostasis, especially under stress conditions such as heat shock. HSP 70 is not only essential for protein quality control but also participates in the translocation of proteins across cellular membranes, thereby influencing various cellular processes. HSP 70 expression is significantly upregulated in response to stress, highlighting its importance in protecting cells from damage and ensuring survival during adverse conditions. Additionally, HSP 70 interacts with several other proteins, including HSC 70, which further enhances its role in the chaperoning process and cellular stress response mechanisms.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HSP70 Antibody (C92F3A-5) has 126 citations in a variety of scientific publications.

Primary antibodies like Anti-HSP70 Antibody (C92F3A-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HSP70 Antibody (C92F3A-5) Specifications

Alternate Product Name: heat shock protein A (Hsp70)

Product Clone Name: C92F3A-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids: 436-503

Epitope Target: HSP 70

Epitope Species: human

Product Reactivity/Detection: HSP 70

Species Reactivity/Detection: mouse, rat, human, bovine, porcine, canine, Drosophila, C. elegans

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 50% glycerol

Research Citations: 126 citations in various scientific publications

Available Conjugates/Forms for HSP70 Antibody (C92F3A-5): N/A

The preferred HSC70/HSP70 antibody is HSC70/HSP70 Antibody (W27): sc-24.