Date published: 2026-4-24

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HSP 105 Inhibitors

HSP105 inhibitors form a chemical class of compounds that and reversibly target HSP105 (Heat Shock Protein 105), a member of the heat shock protein family. HSP105 plays essential roles as a molecular chaperone, assisting in protein folding and protecting cells from stress-induced damage. These inhibitors are specifically engineered to interact with HSP105, aiming to disrupt its chaperone function and modulate cellular processes influenced by HSP105 activity. The chemical structure of HSP105 inhibitors allows them to bind to specific regions or binding sites on the protein, potentially interfering with its ability to facilitate proper protein folding. Researchers utilize HSP105 inhibitors in biochemical and cellular studies to investigate the functions of HSP105 and its implications in various biological contexts, particularly in response to cellular stress. The design and development of these inhibitors rely on a comprehensive understanding of HSP105's structural features and its involvement in cellular stress response and proteostasis, providing valuable tools for advancing research in the field of cellular biology and chaperone-mediated processes.

Items 1 to 10 of 13 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Heat Shock Protein Inhibitor I

218924-25-5sc-221709
5 mg
$97.00
5
(1)

Heat Shock Protein Inhibitor I (CAS 218924-25-5) is a small molecule compound that acts as an inhibitor of HSP 105, a member of the HSP70 family of heat shock proteins. It specifically targets HSP 105's ATPase activity, essential for its chaperone function, thereby disrupting its ability to facilitate protein folding and cellular stress response. As a research tool, it provides insights into the role of HSP 105 in cellular processes without implying any specific applications.

Novobiocin

303-81-1sc-362034
sc-362034A
5 mg
25 mg
$128.00
$380.00
(0)

Novobiocin is an antibiotic that has been reported to inhibit the interaction between Hsp10 and Hsp60.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$97.00
$328.00
$676.00
$1467.00
6
(1)

Rifampicin is an antibiotic known to interfere with the function of bacterial Hsp60-Hsp10 complexes.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin is a flavonoid compound found in various plants that has been studied for its inhibitory effects on Hsp10.

Radicicol

12772-57-5sc-200620
sc-200620A
1 mg
5 mg
$92.00
$333.00
13
(1)

Radicicol is a natural compound that has been reported to inhibit Hsp10 function in vitro.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$39.00
$59.00
$104.00
$206.00
8
(1)

Geldanamycin is a natural compound known for its inhibitory effects on heat shock proteins, including Hsp10.

Mitoxantrone

65271-80-9sc-207888
100 mg
$285.00
8
(1)

Mitoxantrone is an anthracenedione antineoplastic agent that has been studied for its effects on Hsp10.

Apigenin

520-36-5sc-3529
sc-3529A
sc-3529B
sc-3529C
sc-3529D
sc-3529E
sc-3529F
5 mg
100 mg
1 g
5 g
25 g
100 g
1 kg
$33.00
$214.00
$734.00
$1151.00
$2348.00
$3127.00
$5208.00
22
(1)

Apigenin is a natural flavone found in plants that has been reported to inhibit Hsp10 activity.

Etoposide 3′,4′-Quinone

105016-65-7sc-497426
50 mg
$380.00
(0)

Etoposide 3',4'-Quinone has been studied for their inhibitory effects on Hsp10 function.

Myricetin

529-44-2sc-203147
sc-203147A
sc-203147B
sc-203147C
sc-203147D
25 mg
100 mg
1 g
25 g
100 g
$97.00
$188.00
$260.00
$510.00
$1022.00
3
(1)

Myricetin is a flavonoid compound found in various fruits and vegetables that has been investigated for its effects on Hsp10.