Date published: 2026-1-19

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HSF Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of HSF Antibodies for advanced research in the field of heat shock proteins. HSF Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Heat shock factors (HSFs) play a crucial role in cellular stress responses, regulating the expression of heat shock proteins that assist in protein folding and protection against stress-induced damage. The importance of HSFs extends to various physiological processes, including development, aging, and disease states. Understanding HSF regulation and function is essential for advancing research in cellular responses to environmental changes. HSF research has revealed significant insights into stress response mechanisms and their impact on cellular health. Investigating HSFs has led to important discoveries about protein quality control and cellular adaptation mechanisms. Researchers worldwide rely on Santa Cruz Biotechnology monoclonal antibodies to advance scientific understanding of heat shock response pathways and their implications in human health and disease.

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HSF Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HSF1 Antibody (E-4)

sc-17757mouse IgG1 κ219-529 (h)WB, IP, IF, IHC(P), ELISAm, r, h
49
(19)

HSF1 Antibody (10H8)

sc-13516rat IgG1378-395 (m)WB, IP, IF, IHC(P)m, r, h
18
(11)

HSF1 Antibody (C-5)

sc-17756mouse IgG2b κ219-529 (h)WB, IP, IF, IHC(P), ELISAm, r, h
11
(6)

HSF1 Antibody (A-7)

sc-393677mouse IgG2b κ504-529 (h)WB, IP, IF, ELISAm, r, h

new

(1)

HSF1 Antibody (C-9)

sc-393509mouse IgG1 κ508-529 (h)WB, IP, IF, ELISAm, r, h

new

(3)

HSF2 Antibody (G-11)

sc-74529mouse IgG1 κ237-536 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(8)

HSF2 Antibody (3E2)

sc-13517rat IgG2aFL (m)WB, IP, IF, IHC(P), ELISAm, r, h
6
(3)

HSF2 Antibody (E-2)

sc-377045mouse IgG3 κ507-536 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

HSF2BP Antibody (5)

sc-130322mouse IgG1 κ(h)WB, ELISAh
1
(1)

HSF4 Antibody (A-12)

sc-398645mouse IgG1 κ120-244 (h)WB, IP, IF, ELISAm, r, h
1
(2)

HSF CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSF1 CRISPR/Cas9 KO Plasmid (h2)

sc-400432-KO-2hGene KnockoutGFP
1
(0)

HSF1 Double Nickase Plasmid (h)

sc-400432-NIChGene KnockoutPuromycin
1
(0)

HSF1 Double Nickase Plasmid (h2)

sc-400432-NIC-2hGene KnockoutPuromycin
1
(0)

HSF1 CRISPR/Cas9 KO Plasmid (m)

sc-420971mGene KnockoutGFP0
(0)

HSF1 HDR Plasmid (m)

sc-420971-HDRmHomology Directed RepairPuromycin0
(0)

HSF1 Double Nickase Plasmid (m)

sc-420971-NICmGene KnockoutPuromycin0
(0)

HSF1 Double Nickase Plasmid (m2)

sc-420971-NIC-2mGene KnockoutPuromycin0
(0)

HSF2 CRISPR/Cas9 KO Plasmid (h)

sc-402400hGene KnockoutGFP0
(0)

HSF2 HDR Plasmid (h)

sc-402400-HDRhHomology Directed RepairPuromycin0
(0)

HSF2 Double Nickase Plasmid (h)

sc-402400-NIChGene KnockoutPuromycin0
(0)

HSF2 Double Nickase Plasmid (h2)

sc-402400-NIC-2hGene KnockoutPuromycin0
(0)

HSF4 Double Nickase Plasmid (h)

sc-403850-NIChGene KnockoutPuromycin0
(0)

HSF4 Double Nickase Plasmid (h2)

sc-403850-NIC-2hGene KnockoutPuromycin0
(0)

HSF CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSF1 CRISPR Activation Plasmid (h)

sc-400432-ACThGene ActivationPuro, Blast, Hygro
1
(0)

HSF1 Lentiviral Activation Particles (h)

sc-400432-LAChGene ActivationPuro, Blast, Hygro
1
(0)

HSF2 CRISPR Activation Plasmid (h)

sc-402400-ACThGene ActivationPuro, Blast, Hygro0
(0)

HSF2 CRISPR Activation Plasmid (h2)

sc-402400-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

HSF4 CRISPR Activation Plasmid (h)

sc-403850-ACThGene ActivationPuro, Blast, Hygro0
(0)

HSF siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSF1 siRNA (h)

sc-35611hGene SilencingN/A
33
(1)

HSF1 siRNA (m)

sc-35612mGene SilencingN/A
7
(0)

HSF1 siRNA (r)

sc-270440rGene SilencingN/A
2
(0)

HSF1 shRNA Plasmid (r)

sc-270440-SHrGene SilencingPuromycin
2
(0)

HSF1 shRNA (r) Lentiviral Particles

sc-270440-VrGene SilencingPuromycin
2
(0)

HSTF1 shRNA Plasmid (h)

sc-35611-SHhGene SilencingPuromycin
33
(1)

HSTF1 shRNA (h) Lentiviral Particles

sc-35611-VhGene SilencingPuromycin
33
(1)

HSTF1 shRNA Plasmid (m)

sc-35612-SHmGene SilencingPuromycin
7
(0)

HSTF1 shRNA (m) Lentiviral Particles

sc-35612-VmGene SilencingPuromycin
7
(0)

HSF2 siRNA (h)

sc-35613hGene SilencingN/A
1
(0)

HSF2 shRNA Plasmid (h)

sc-35613-SHhGene SilencingPuromycin
1
(0)

HSF2 shRNA (h) Lentiviral Particles

sc-35613-VhGene SilencingPuromycin
1
(0)

HSF2 siRNA (m)

sc-35614mGene SilencingN/A0
(0)

HSF2BP siRNA (h)

sc-62480hGene SilencingN/A0
(0)

HSF2BP shRNA Plasmid (h)

sc-62480-SHhGene SilencingPuromycin0
(0)

HSF2BP shRNA (h) Lentiviral Particles

sc-62480-VhGene SilencingPuromycin0
(0)

HSTF2 shRNA Plasmid (m)

sc-35614-SHmGene SilencingPuromycin0
(0)

HSTF2 shRNA (m) Lentiviral Particles

sc-35614-VmGene SilencingPuromycin0
(0)

HSF3 siRNA (m)

sc-141440mGene SilencingN/A0
(0)

HSF3 shRNA Plasmid (m)

sc-141440-SHmGene SilencingPuromycin0
(0)

HSF3 shRNA (m) Lentiviral Particles

sc-141440-VmGene SilencingPuromycin0
(0)

HSF4 siRNA (h)

sc-37924hGene SilencingN/A
1
(0)

HSF4 shRNA Plasmid (h)

sc-37924-SHhGene SilencingPuromycin
1
(0)

HSF4 shRNA (h) Lentiviral Particles

sc-37924-VhGene SilencingPuromycin
1
(0)

HSF4 siRNA (m)

sc-37925mGene SilencingN/A0
(0)

HSF4 shRNA Plasmid (m)

sc-37925-SHmGene SilencingPuromycin0
(0)

HSF4 shRNA (m) Lentiviral Particles

sc-37925-VmGene SilencingPuromycin0
(0)

HSF5 siRNA (h)

sc-105542hGene SilencingN/A0
(0)

HSF5 shRNA Plasmid (h)

sc-105542-SHhGene SilencingPuromycin0
(0)

HSF5 shRNA (h) Lentiviral Particles

sc-105542-VhGene SilencingPuromycin0
(0)

HSF5 siRNA (m)

sc-105543mGene SilencingN/A0
(0)

HSF5 shRNA Plasmid (m)

sc-105543-SHmGene SilencingPuromycin0
(0)

HSF5 shRNA (m) Lentiviral Particles

sc-105543-VmGene SilencingPuromycin0
(0)

HSF Transfected Lysates

Empty Table HeaderProduct NameCATALOG #SpeciesCONTROL ANTIBODYCitationsRATING

HSF1 (h): 293T Lysate

sc-171930h0
(0)