HSF1 Antibody (C-9): sc-393509
- HSF1 Antibody (C-9) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 508-529 at the C-terminus of HSF1 of human origin
- recommended for detection of HSF1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine
- TransCruz reagent for ChIP application (sc-393509 X, 200 µg/0.1 ml)
- See HSF1 (E-4): sc-17757 for HSF1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for HSF1 Antibody (C-9) for WB applications. These reagents are now offered in bundles with HSF1 Antibody (C-9) (see ordering information below).
QUICK LINKS
HSF1 Antibody (C-9) is a mouse monoclonal IgG1 antibody that detects heat shock factor 1 (HSF1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HSF1 plays a crucial role in the cellular response to stress by regulating the expression of heat shock proteins, which are essential for protein folding and protection against aggregation during stressful conditions. HSF1 is primarily located in the cytoplasm as a monomer under normal conditions, but upon stress, undergoes a conformational change, forming trimers that translocate to the nucleus to activate heat shock gene transcription. The ability of HSF1 to switch from a repressed state to an active transcription factor is vital for cellular survival during thermal and chemical stress, making HSF1 a key player in maintaining proteostasis and cellular homeostasis. Anti-HSF1 antibody (C-9) is an invaluable tool for researchers studying stress responses, protein homeostasis, and the regulatory mechanisms of heat shock proteins in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSF1 Antibody (C-9) | sc-393509 | 200 µg/ml | $322.00 | |||
HSF1 Antibody (C-9): m-IgG Fc BP-HRP Bundle | sc-540903 | 200 µg Ab; 10 µg BP | $361.00 | |||
HSF1 Antibody (C-9): m-IgG1 BP-HRP Bundle | sc-542454 | 200 µg Ab; 20 µg BP | $361.00 | |||
HSF1 (C-9) Neutralizing Peptide | sc-393509 P | 100 µg/0.5 ml | $69.00 | |||
HSF1 Antibody (C-9) X | sc-393509 X | 200 µg/0.1 ml | $322.00 |