Date published: 2026-5-6

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HSF1 Antibodies

Santa Cruz Biotechnology provides a broad selection of HSF1 monoclonal antibodies for investigating heat shock response and cellular stress mechanisms. HSF1 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HSF1, or Heat Shock Factor 1, plays a central role in regulating heat shock proteins, which are essential for protein folding and protection against stress-induced damage. HSF1 maintains cellular homeostasis and influences various diseases, including neurodegenerative disorders and cancer. Research focused on HSF1 can reveal potential therapeutic strategies for modulating stress responses in cells. Studying HSF1 activity helps scientists understand cellular adaptation mechanisms under various stress conditions. HSF1 research contributes to developing new approaches for treating stress-related pathologies. Understanding HSF1 regulation provides valuable insights into cellular defense mechanisms and stress response pathways. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of HSF1's role in health and disease.

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HSF1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HSF1 Antibody (E-4)

sc-17757mouse IgG1 κ219-529 (h)WB, IP, IF, IHC(P), ELISAm, r, h
49
(19)

HSF1 Antibody (10H8)

sc-13516rat IgG1378-395 (m)WB, IP, IF, IHC(P)m, r, h
18
(11)

HSF1 Antibody (C-5)

sc-17756mouse IgG2b κ219-529 (h)WB, IP, IF, IHC(P), ELISAm, r, h
11
(7)

HSF1 Antibody (A-7)

sc-393677mouse IgG2b κ504-529 (h)WB, IP, IF, ELISAm, r, h

new

(1)

HSF1 Antibody (C-9)

sc-393509mouse IgG1 κ508-529 (h)WB, IP, IF, ELISAm, r, h

new

(3)

HSF1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSF1 CRISPR/Cas9 KO Plasmid (h2)

sc-400432-KO-2hGene KnockoutGFP
1
(0)

HSF1 Double Nickase Plasmid (h)

sc-400432-NIChGene KnockoutPuromycin
1
(0)

HSF1 Double Nickase Plasmid (h2)

sc-400432-NIC-2hGene KnockoutPuromycin
1
(0)

HSF1 CRISPR/Cas9 KO Plasmid (m)

sc-420971mGene KnockoutGFP0
(0)

HSF1 HDR Plasmid (m)

sc-420971-HDRmHomology Directed RepairPuromycin0
(0)

HSF1 Double Nickase Plasmid (m)

sc-420971-NICmGene KnockoutPuromycin0
(0)

HSF1 Double Nickase Plasmid (m2)

sc-420971-NIC-2mGene KnockoutPuromycin0
(0)

HSF1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSF1 CRISPR Activation Plasmid (h)

sc-400432-ACThGene ActivationPuro, Blast, Hygro
1
(0)

HSF1 Lentiviral Activation Particles (h)

sc-400432-LAChGene ActivationPuro, Blast, Hygro
1
(0)

HSF1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSF1 siRNA (h)

sc-35611hGene SilencingN/A
33
(1)

HSF1 siRNA (m)

sc-35612mGene SilencingN/A
7
(0)

HSF1 siRNA (r)

sc-270440rGene SilencingN/A
2
(0)

HSF1 shRNA Plasmid (r)

sc-270440-SHrGene SilencingPuromycin
2
(0)

HSF1 shRNA (r) Lentiviral Particles

sc-270440-VrGene SilencingPuromycin
2
(0)

HSTF1 shRNA Plasmid (h)

sc-35611-SHhGene SilencingPuromycin
33
(1)

HSTF1 shRNA (h) Lentiviral Particles

sc-35611-VhGene SilencingPuromycin
33
(1)

HSTF1 shRNA Plasmid (m)

sc-35612-SHmGene SilencingPuromycin
7
(0)

HSTF1 shRNA (m) Lentiviral Particles

sc-35612-VmGene SilencingPuromycin
7
(0)