HPV16 L1 Activators
HPV16 L1 activators constitute a specific category of chemical compounds that interact with the HPV16 L1 protein, a critical component of the human papillomavirus type 16 (HPV16) viral particle. HPV16 is a member of the Papillomaviridae family and is one of the most common high-risk HPV types associated with cervical cancer and other malignancies. The L1 protein forms the major capsid structure of the HPV virion, and its assembly is essential for the viral life cycle, including the infection of host epithelial cells. When activated by specific compounds, HPV16 L1 protein may undergo conformational changes or interactions that influence its ability to self-assemble into viral capsids, facilitating the formation of infectious viral particles.
Understanding the activation of HPV16 L1 is critical for elucidating the mechanisms of HPV infection and the development of potential preventative strategies. HPV16 is a significant public health concern due to its association with various cancers and the development of vaccines targeting the L1 protein to prevent infection. Activators of HPV16 L1 can be instrumental in studying the structural and functional aspects of viral capsid formation, shedding light on the processes involved in HPV infection and the design of effective vaccines. Research in this area contributes to a broader understanding of viral biology and the development of preventive measures against HPV-associated diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a metabolite of vitamin A, can influence cellular differentiation and proliferation, potentially affecting the expression of HPV16 L1 by altering the cellular environment conducive to viral replication. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This compound, found in green tea, has been shown to have antiviral properties and may influence HPV16 L1 expression by interfering with viral replication processes. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Cisplatin can induce cellular stress responses, potentially leading to changes in viral protein expression including HPV16 L1. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-Azacytidine may affect the epigenetic regulation of viral genes, potentially impacting HPV16 L1 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, found in turmeric, has multiple biological activities, including effects on cell signaling pathways that might influence HPV16 L1 expression. | ||||||
Acyclovir | 59277-89-3 | sc-202906 sc-202906A | 50 mg 500 mg | $147.00 $922.00 | 2 | |
Acyclovir might affect HPV replication indirectly, thereby influencing HPV16 L1 expression levels. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a compound in red wine, has various biological effects and could modulate viral protein expression, including HPV16 L1, through its action on cellular pathways. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As a histone deacetylase inhibitor, Sodium Butyrate can affect chromatin structure and gene expression, potentially influencing HPV16 L1 expression. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin can induce a variety of cellular responses that might affect viral protein expression including HPV16 L1. | ||||||
Levamisole Hydrochloride | 16595-80-5 | sc-205730 sc-205730A | 5 g 10 g | $42.00 $67.00 | 18 | |
Levamisole Hydrochloride, an immunomodulator, could potentially influence HPV16 L1 expression through modulation of the immune response. | ||||||