hnRNP I Activators
Heterogeneous nuclear ribonucleoprotein I (hnRNP I), also known as polypyrimidine tract-binding protein (PTB), has a critical role in the regulation of gene expression at the post-transcriptional level. hnRNP I activators are a class of molecules that can influence the activity or increase the expression of this protein. These compounds can modulate several aspects of mRNA metabolism, including alternative splicing, polyadenylation, and mRNA stability, by affecting hnRNP I activity.
The specific mechanism by which hnRNP I activators function can vary widely. Some may interact directly with the hnRNP I protein, enhancing its binding to polypyrimidine tracts and thus influencing mRNA processing. Others may affect the transcription or translation processes of the hnRNP I gene, thereby increasing the cellular level of hnRNP I. Additional compounds might influence upstream or downstream signaling pathways that indirectly modulate hnRNP I activity. For example, some hnRNP I activators may affect cellular stress response pathways, which could, in turn, impact the role of hnRNP I in these responses. Regardless of their specific mechanisms, all hnRNP I activators share the common feature of enhancing the activity or expression of hnRNP I in some manner. They provide valuable tools for studying the complex processes of mRNA metabolism and the role of hnRNP I in these processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D might induce hnRNP I expression as part of its broad effects on cellular regulation and response to stress. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide could potentially modulate hnRNP I expression through its action on protein synthesis inhibition. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide might influence hnRNP I expression due to its DNA damage inducing properties. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
Fluorouracil might modulate hnRNP I expression due to its interactions with RNA metabolism. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine might influence hnRNP I expression through its effects on DNA methylation. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin could potentially upregulate hnRNP I due to its action on DNA repair mechanisms. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin could potentially induce hnRNP I expression as part of its effects on DNA intercalation and topoisomerase II inhibition. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine could potentially induce hnRNP I expression due to its potent effects on various kinases. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A might enhance hnRNP I expression via its histone deacetylase (HDAC) inhibitory properties. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate could potentially induce hnRNP I expression due to its HDAC inhibitory properties. | ||||||