Date published: 2026-7-10

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HMG CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. HMG gene silencers are available as HMG CRISPR/Cas9 Knockout plasmids and HMG Double Nickase Plasmids. HMG CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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HMG CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

HMG-1/HMGB1 CRISPR/Cas9 KO Plasmid (h)

sc-400735Gene Knockouth0
(0)

HMGI-C CRISPR/Cas9 KO Plasmid (h)

sc-401573Gene Knockouth0
(0)

HMG-I/HMG-Y CRISPR/Cas9 KO Plasmid (h)

sc-402396Gene Knockouth0
(0)

HMG-20A CRISPR/Cas9 KO Plasmid (h)

sc-407302Gene Knockouth0
(0)

HMG-3/HMGB3 CRISPR/Cas9 KO Plasmid (m)

sc-420875Gene Knockoutm0
(0)

HMGI-C CRISPR/Cas9 KO Plasmid (m)

sc-420880Gene Knockoutm0
(0)

HMG-1/HMGB1 HDR Plasmid (h)

sc-400735-HDRHomology Directed Repairh0
(0)

HMGI-C HDR Plasmid (h)

sc-401573-HDRHomology Directed Repairh0
(0)

HMGI-C HDR Plasmid (m)

sc-420880-HDRHomology Directed Repairm0
(0)

HMG-1/HMGB1 CRISPR/Cas9 KO Plasmid (m2)

sc-420871-KO-2Gene Knockoutm0
(0)

HMG-I/HMG-Y CRISPR/Cas9 KO Plasmid (m2)

sc-420879-KO-2Gene Knockoutm0
(0)

HMG-1/HMGB1 HDR Plasmid (m2)

sc-420871-HDR-2Homology Directed Repairm0
(0)

HMG-I/HMG-Y HDR Plasmid (m2)

sc-420879-HDR-2Homology Directed Repairm0
(0)

HMG CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

HMG-1/HMGB1 Double Nickase Plasmid (h)

sc-400735-NICGene Knockouth0
(0)

HMG-I/HMG-Y Double Nickase Plasmid (h)

sc-402396-NICGene Knockouth0
(0)

HMG-2/HMGB2 Double Nickase Plasmid (h)

sc-404000-NICGene Knockouth0
(0)

HMG-1/HMGB1 Double Nickase Plasmid (m)

sc-420871-NICGene Knockoutm0
(0)

HMG-I/HMG-Y Double Nickase Plasmid (m)

sc-420879-NICGene Knockoutm0
(0)

HMG-1/HMGB1 Double Nickase Plasmid (h2)

sc-400735-NIC-2Gene Knockouth0
(0)

HMG-I/HMG-Y Double Nickase Plasmid (h2)

sc-402396-NIC-2Gene Knockouth0
(0)

HMG-2/HMGB2 Double Nickase Plasmid (h2)

sc-404000-NIC-2Gene Knockouth0
(0)

HMG-1/HMGB1 Double Nickase Plasmid (m2)

sc-420871-NIC-2Gene Knockoutm0
(0)

HMG-I/HMG-Y Double Nickase Plasmid (m2)

sc-420879-NIC-2Gene Knockoutm0
(0)

HMG CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

HMG-1/HMGB1 CRISPR Activation Plasmid (h)

sc-400735-ACTGene Activationh0
(0)

HMGI-C CRISPR Activation Plasmid (h)

sc-401573-ACTGene Activationh0
(0)

HMG-1/HMGB1 CRISPR Activation Plasmid (m)

sc-420871-ACTGene Activationm0
(0)

HMGI-C CRISPR Activation Plasmid (m)

sc-420880-ACTGene Activationm0
(0)

HMG-1/HMGB1 CRISPR Activation Plasmid (h2)

sc-400735-ACT-2Gene Activationh0
(0)

HMG-1/HMGB1 CRISPR Activation Plasmid (m2)

sc-420871-ACT-2Gene Activationm0
(0)

HMGI-C CRISPR Activation Plasmid (m2)

sc-420880-ACT-2Gene Activationm0
(0)

HMGI-C Lentiviral Activation Particles (m)

sc-420880-LACGene Activationm0
(0)

HMGI-C Lentiviral Activation Particles (m2)

sc-420880-LAC-2Gene Activationm0
(0)