Histone cluster 2 H3D Inhibitors
Histone cluster 2 H3D inhibitors constitute a distinctive chemical class tailored to selectively target and modulate the function of H3D histone proteins. As a variant within the histone cluster 2 family, H3D plays a pivotal role in shaping chromatin architecture and influencing gene regulation. Functioning as a key component of nucleosomes, H3D contributes to the compact organization of DNA, intricately participating in the regulation of gene expression dynamics. The inhibitors developed for Histone cluster 2 H3D are meticulously designed to interact with the specific molecular structure of this histone variant, aiming to disrupt its normal interactions within the nucleosome and potentially bring about alterations in the broader chromatin landscape.
The molecular architecture of Histone cluster 2 H3D inhibitors is intricately crafted, targeting precise binding sites on H3D to induce changes in its conformation and dynamics. This interaction holds the potential to impact the accessibility of DNA, thereby influencing the intricate processes governing gene expression. In laboratory settings, researchers utilize these inhibitors as powerful tools to delve into the nuanced roles of H3D in various cellular processes, contributing to a deeper understanding of chromatin biology. By manipulating the function of H3D, scientists aim to unravel the intricate mechanisms of gene regulation, shedding light on the broader implications of epigenetic processes for cellular function and development. The study of Histone cluster 2 H3D inhibitors thus stands at the forefront of advancing our comprehension of chromatin dynamics and the finely tuned orchestration of gene expression within the cellular milieu.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D intercalates into DNA, disrupting RNA synthesis. This interference with transcription may impede the expression of H3 clustered histone 13. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
Entinostat is a histone deacetylase inhibitor, altering chromatin structure. By inhibiting histone deacetylation, it may interfere with the transcriptional regulation of H3 clustered histone 13. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor, modifying DNA methylation patterns. Changes in methylation status can influence gene expression, potentially affecting the transcription of H3 clustered histone 13. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
Nicotinamide acts as a histone deacetylase inhibitor. Its ability to influence chromatin structure may interfere with the transcriptional regulation of H3 clustered histone 13. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin forms DNA adducts, inducing DNA damage. This damage response can affect transcription, potentially influencing the expression of H3 clustered histone 13. | ||||||
Tris Buffered Saline: 1 L of 1X | sc-362185 | 1 L | $21.00 | 3 | ||
Tubacin is a histone deacetylase 6 (HDAC6) inhibitor. By specifically targeting HDAC6, it may modulate the acetylation status of non-histone proteins, potentially impacting the expression of H3 clustered histone 13. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Decitabine is a DNA methyltransferase inhibitor, altering DNA methylation patterns. Changes in methylation status can influence gene expression, potentially affecting the transcription of H3 clustered histone 13. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Ellagic acid exhibits antioxidant properties and may influence transcription factors. Its interaction with these factors may impact the expression of H3 clustered histone 13. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Camptothecin inhibits topoisomerase I, inducing DNA damage. This damage response can disrupt transcription, potentially influencing the expression of H3 clustered histone 13. | ||||||
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
RGFP966 is a histone acetyltransferase (HAT) inhibitor. By inhibiting HAT activity, it may modulate chromatin structure and interfere with the transcriptional regulation of H3 clustered histone 13. | ||||||