HHV-4 EBNA-LP Activators
**HHV-4 EBNA-LP activators** are a class of compounds that enhance the expression or activity of the HHV-4 EBNA-LP protein. HHV-4 EBNA-LP is a latent protein expressed during Epstein-Barr virus (EBV) latency. It plays a crucial role in maintaining the viral genome in latently infected cells and in regulating the switch between latency and lytic replication. HHV-4 EBNA-LP activators can increase the levels of HHV-4 EBNA-LP protein, promote its interaction with other proteins, or enhance its activity in regulating viral latency and reactivation.
HHV-4 EBNA-LP activators exert their effect by modulating different aspects of HHV-4 EBNA-LP biology. Some HHV-4 EBNA-LP activators, such as 12-O-Tetradecanoylphorbol-13-acetate (TPA), induce HHV-4 EBNA-LP expression by activating the PKC signaling pathway. Other HHV-4 EBNA-LP activators, such as histone deacetylase inhibitors (sodium butyrate, trichostatin A, valproic acid), induce HHV-4 EBNA-LP expression by inhibiting histone deacetylases. Additionally, some natural compounds, such as resveratrol, quercetin, curcumin, and epigallocatechin gallate (EGCG), have been shown to induce HHV-4 EBNA-LP expression by activating various signaling pathways or transcription factors. By modulating HHV-4 EBNA-LP expression or activity, HHV-4 EBNA-LP activators can influence viral latency and reactivation, and thereby affect the pathogenesis of EBV-associated diseases. These compounds have been instrumental in dissecting the molecular mechanisms underlying HHV-4 EBNA-LP function and its involvement in EBV latency and reactivation.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
A protein kinase C activator that induces HHV-4 EBNA-LP expression by activating the PKC signaling pathway. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A histone deacetylase inhibitor that induces HHV-4 EBNA-LP expression by inhibiting histone deacetylases. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that induces HHV-4 EBNA-LP expression by inhibiting histone deacetylases. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
A histone deacetylase inhibitor that induces HHV-4 EBNA-LP expression by inhibiting histone deacetylases. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A natural polyphenol that induces HHV-4 EBNA-LP expression by activating the SIRT1 deacetylase. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
A natural flavonoid that induces HHV-4 EBNA-LP expression by activating the SIRT1 deacetylase. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A natural compound found in turmeric that induces HHV-4 EBNA-LP expression by activating the SIRT1 deacetylase. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A natural polyphenol found in green tea that induces HHV-4 EBNA-LP expression by activating the SIRT1 deacetylase. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
A natural compound found in cruciferous vegetables that induces HHV-4 EBNA-LP expression by activating the Nrf2 transcription factor. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A natural isoflavone found in soybeans that induces HHV-4 EBNA-LP expression by activating the JAK/STAT signaling pathway. | ||||||