HDAC2 Inhibitors
Santa Cruz Biotechnology now offers a broad range of HDAC2 Inhibitors. Histone deacetylase proteins (HDACs) are a class of enzymes that remove acetyl groups (O=C-CH3) from an <ε>-N-acetyl lysine amino acid on a histone, allowing histones to wrap DNA more tightly. The deacetylation of histones is associated with transcriptional silencing. Histone deacetylase inhibitors (HDIs) have a long history of use in psychiatry and neurology as mood stabilizers and anti-epileptic. HDIs are studied as a treatment for neurodegenerative diseases and have a potential for cancer therapy. HDAC2 Inhibitors offered by Santa Cruz inhibit HDAC2 and, in some cases, other chromatin remodeling and transcription regulation related proteins. View detailed HDAC2 Inhibitor specifications, including HDAC2 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 11 to 16 of 16 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
TC-H 106 | 937039-45-7 | sc-362801 sc-362801A | 10 mg 50 mg | $155.00 $620.00 | ||
TC-H 106 exhibits a distinctive mode of action as an HDAC2 inhibitor, characterized by its ability to form covalent bonds with key amino acid residues within the enzyme's active site. This interaction leads to a conformational shift that enhances substrate accessibility. The compound's unique steric properties facilitate selective binding, while its reaction kinetics suggest a robust affinity, resulting in sustained modulation of histone acetylation dynamics and downstream cellular processes. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
Entinostat is a class I HDAC inhibitor with activity against HDAC2. Its inhibition might affect HDAC2 protein levels in some settings. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
Panobinostat is a pan-HDAC inhibitor with activity against HDAC2. It affects acetylation levels and possibly HDAC2 expression. | ||||||
Apicidin | 183506-66-3 | sc-202061 sc-202061A | 1 mg 5 mg | $110.00 $343.00 | 9 | |
Apicidin is an HDAC inhibitor with activity against HDAC2. By inhibiting its function, apicidin can modulate chromatin structure and gene expression. | ||||||
Belinostat | 414864-00-9 | sc-269851 sc-269851A | 10 mg 100 mg | $156.00 $572.00 | ||
Belinostat is a pan-HDAC inhibitor that inhibits HDAC2. Its action can lead to changes in gene expression and potentially HDAC2 levels. | ||||||
PCI-34051 | 950762-95-5 | sc-364566 sc-364566A | 10 mg 100 mg | $189.00 $1671.00 | 5 | |
PCI-34051 is a selective HDAC8 inhibitor, but it might have off-target effects on HDAC2. Its inhibition can lead to changes in chromatin structure and gene expression. | ||||||