Date published: 2025-10-15

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H2-M10.3 Inhibitors

H2-M10.3 inhibitors constitute a specific category of chemical compounds designed to modulate the activity of the H2-M10.3 protein. H2-M10.3, also known as histocompatibility 2, M region locus 10.3, is a protein that is a part of the major histocompatibility complex (MHC) in mice. The MHC system plays a pivotal role in the immune response by presenting antigenic peptides to T cells, allowing the immune system to recognize and respond to foreign pathogens. H2-M10.3, like other MHC molecules, is involved in this process of antigen presentation, which is fundamental for the body's ability to initiate immune responses against infections. The development of H2-M10.3 inhibitors is driven by the primary objective of selectively interacting with the H2-M10.3 protein, potentially influencing its antigen-presenting activity and impacting immune recognition processes.

H2-M10.3 inhibitors are typically composed of small molecules or chemical compounds specifically designed to bind to H2-M10.3, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2-M10.3's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are primarily dedicated to unraveling the molecular mechanisms and functions of H2-M10.3 within the MHC system and how inhibiting its activity with these compounds may provide insights into the intricate immune recognition processes. The development of H2-M10.3 inhibitors represents an active area of research within the fields of immunology and molecular pharmacology, contributing to a deeper understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

This cytidine analog may incorporate into DNA during replication, potentially leading to hypomethylation and affecting gene expression.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

RG108 is a DNA methyltransferase inhibitor, potentially resulting in DNA demethylation and altered gene transcription.

Zebularine

3690-10-6sc-203315
sc-203315A
sc-203315B
10 mg
25 mg
100 mg
$126.00
$278.00
$984.00
3
(1)

Zebularine acts as a DNA methyltransferase inhibitor, which might lead to changes in gene expression through epigenetic modifications.

1-β-D-Arabinofuranosylcytosine

147-94-4sc-201628
sc-201628A
sc-201628B
sc-201628C
sc-201628D
1 g
5 g
25 g
100 g
250 g
$147.00
$258.00
$508.00
$717.00
$1432.00
1
(1)

1-β-D-Arabinofuranosylcytosine is a nucleoside analog that can be incorporated into DNA, potentially disrupting DNA synthesis and gene expression.

Hydroxyurea

127-07-1sc-29061
sc-29061A
5 g
25 g
$76.00
$255.00
18
(1)

Hydroxyurea inhibits ribonucleotide reductase, which might lead to a reduction in DNA synthesis and gene expression.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

Flavopiridol inhibits cyclin-dependent kinases, potentially affecting cell cycle progression and gene expression.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein is a tyrosine kinase inhibitor, which may modulate signal transduction pathways influencing gene expression.

Sodium phenylbutyrate

1716-12-7sc-200652
sc-200652A
sc-200652B
sc-200652C
sc-200652D
1 g
10 g
100 g
1 kg
10 kg
$75.00
$163.00
$622.00
$4906.00
$32140.00
43
(1)

Phenylbutyrate is a histone deacetylase inhibitor, which can influence chromatin structure and gene expression.

Oxamflatin

151720-43-3sc-205960
sc-205960A
1 mg
5 mg
$148.00
$461.00
4
(1)

Oxamflatin is a histone deacetylase inhibitor, potentially affecting the chromatin state and gene transcription.

Apicidin

183506-66-3sc-202061
sc-202061A
1 mg
5 mg
$108.00
$336.00
9
(1)

Apicidin is a cyclic tetrapeptide that inhibits histone deacetylase, which can lead to changes in chromatin structure and gene transcription.