H2-M10.3 inhibitors constitute a specific category of chemical compounds designed to modulate the activity of the H2-M10.3 protein. H2-M10.3, also known as histocompatibility 2, M region locus 10.3, is a protein that is a part of the major histocompatibility complex (MHC) in mice. The MHC system plays a pivotal role in the immune response by presenting antigenic peptides to T cells, allowing the immune system to recognize and respond to foreign pathogens. H2-M10.3, like other MHC molecules, is involved in this process of antigen presentation, which is fundamental for the body's ability to initiate immune responses against infections. The development of H2-M10.3 inhibitors is driven by the primary objective of selectively interacting with the H2-M10.3 protein, potentially influencing its antigen-presenting activity and impacting immune recognition processes.
H2-M10.3 inhibitors are typically composed of small molecules or chemical compounds specifically designed to bind to H2-M10.3, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2-M10.3's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are primarily dedicated to unraveling the molecular mechanisms and functions of H2-M10.3 within the MHC system and how inhibiting its activity with these compounds may provide insights into the intricate immune recognition processes. The development of H2-M10.3 inhibitors represents an active area of research within the fields of immunology and molecular pharmacology, contributing to a deeper understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
This cytidine analog may incorporate into DNA during replication, potentially leading to hypomethylation and affecting gene expression. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
RG108 is a DNA methyltransferase inhibitor, potentially resulting in DNA demethylation and altered gene transcription. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $126.00 $278.00 $984.00 | 3 | |
Zebularine acts as a DNA methyltransferase inhibitor, which might lead to changes in gene expression through epigenetic modifications. | ||||||
1-β-D-Arabinofuranosylcytosine | 147-94-4 | sc-201628 sc-201628A sc-201628B sc-201628C sc-201628D | 1 g 5 g 25 g 100 g 250 g | $147.00 $258.00 $508.00 $717.00 $1432.00 | 1 | |
1-β-D-Arabinofuranosylcytosine is a nucleoside analog that can be incorporated into DNA, potentially disrupting DNA synthesis and gene expression. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea inhibits ribonucleotide reductase, which might lead to a reduction in DNA synthesis and gene expression. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol inhibits cyclin-dependent kinases, potentially affecting cell cycle progression and gene expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor, which may modulate signal transduction pathways influencing gene expression. | ||||||
Sodium phenylbutyrate | 1716-12-7 | sc-200652 sc-200652A sc-200652B sc-200652C sc-200652D | 1 g 10 g 100 g 1 kg 10 kg | $75.00 $163.00 $622.00 $4906.00 $32140.00 | 43 | |
Phenylbutyrate is a histone deacetylase inhibitor, which can influence chromatin structure and gene expression. | ||||||
Oxamflatin | 151720-43-3 | sc-205960 sc-205960A | 1 mg 5 mg | $148.00 $461.00 | 4 | |
Oxamflatin is a histone deacetylase inhibitor, potentially affecting the chromatin state and gene transcription. | ||||||
Apicidin | 183506-66-3 | sc-202061 sc-202061A | 1 mg 5 mg | $108.00 $336.00 | 9 | |
Apicidin is a cyclic tetrapeptide that inhibits histone deacetylase, which can lead to changes in chromatin structure and gene transcription. |