H2-M10.3 Activators form a distinct class of chemical entities known for their specific ability to interact with and activate the H2-M10.3 protein. This protein is a part of a broader family of proteins that are integral to various biological functions within cellular systems. The unique characteristic of H2-M10.3 Activators is their targeted action on this specific protein, influencing an array of biochemical pathways integral to cellular processes. These activators are structurally diverse, encompassing various molecular architectures. This diversity is critical to their functional role, as it directly affects their binding affinity and activation potency for the H2-M10.3 protein. The design and synthesis of H2-M10.3 Activators are often guided by intricate structure-activity relationships, highlighting the importance of certain molecular features in their interaction with the target protein. This high degree of specificity in their interaction with H2-M10.3 underscores the sophisticated nature of these compounds in probing and understanding protein functionality.
At the molecular level, the interaction of H2-M10.3 Activators with the H2-M10.3 protein is a significant area of interest in the fields of biochemistry and molecular biology. This interaction typically involves the binding of the activator to a specific site on the H2-M10.3 protein, leading to a conformational change that triggers the activation of the protein. The activation of H2-M10.3 can have far-reaching effects on various cellular processes, accentuating the importance of these activators in the realm of cellular biochemistry. The precision with which H2-M10.3 Activators target the H2-M10.3 protein makes them a focal point in research concerning protein-ligand interactions and the resulting biological effects. Moreover, the study of these activators contributes significantly to the broader understanding of how small molecules can regulate protein function. This research sheds light on the complex mechanisms of protein activation and regulation, offering insights into the intricate network of molecular interactions within cells. Understanding the interaction of H2-M10.3 Activators with their target protein provides valuable information on the dynamic nature of protein function and the potential ways in which these functions can be modulated by specific molecular entities.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can modulate gene transcription via retinoic acid receptors, which could lead to changes in MHC class I gene expression. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3, through its active metabolite, can influence the transcription of immune-related genes by binding to the vitamin D receptor. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that can increase chromatin accessibility, potentially enhancing MHC gene expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane can activate Nrf2, a transcription factor that regulates the expression of various genes including those in the immune system. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin is known to modulate NF-κB signaling, which could impact the transcription of immune-related genes, including MHC class I. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol may activate SIRT1, which is involved in histone deacetylation and could affect MHC class I gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a component of green tea, can influence multiple signaling pathways and might modulate MHC class I gene expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone acts on glucocorticoid receptors and can alter the transcription of genes involved in immune responses. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
DMSO can affect cell permeability and may indirectly influence gene expression through modulation of cellular signaling. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid is another histone deacetylase inhibitor that can lead to an open chromatin state and potentially affect gene expression. | ||||||