The chemical class of Grim19 Inhibitors includes a range of compounds that can indirectly influence the function of Grim19 by targeting various components of the mitochondrial electron transport chain and related processes. These inhibitors do not directly interact with Grim19 but impact its function within the complex mitochondrial network.
Inhibitors like Rotenone, Piericidin A, and Amytal target complex I, where Grim19 is involved, potentially impairing its function by disrupting electron transport. Antimycin A, Atovaquone, and Carboxin, targeting complex III, and Sodium azide and Cyanide, targeting complex IV, also disrupt the electron transport chain, indirectly affecting Grim19's role. Oligomycin, an inhibitor of ATP synthase, can indirectly impact Grim19 by disrupting the overall efficiency of mitochondrial ATP production. Similarly, TTFA and Malonate, which inhibit complex II, affect the electron transport chain and hence could indirectly impact Grim19. Paraquat, known for generating reactive oxygen species, represents a unique approach to disrupting mitochondrial function, which could indirectly affect Grim19.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
An inhibitor of mitochondrial complex I, could indirectly inhibit Grim19 by impairing electron transport chain function. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
Inhibits complex III, potentially impacting the function of Grim19 as part of the electron transport chain. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Inhibits ATP synthase (complex V), could indirectly affect Grim19 by disrupting mitochondrial ATP production. | ||||||
Piericidin A | 2738-64-9 | sc-202287 | 2 mg | $291.00 | 24 | |
A complex I inhibitor, can indirectly affect Grim19 function by inhibiting electron transport. | ||||||
Sodium azide | 26628-22-8 | sc-208393 sc-208393B sc-208393C sc-208393D sc-208393A | 25 g 250 g 1 kg 2.5 kg 100 g | $43.00 $155.00 $393.00 $862.00 $90.00 | 8 | |
Inhibits complex IV, potentially impacting Grim19 indirectly by disrupting electron transport. | ||||||
2-Thenoyltrifluoroacetone | 326-91-0 | sc-251801 | 5 g | $37.00 | 1 | |
Inhibits complex II, potentially affecting Grim19's function indirectly by disrupting the electron transport chain. | ||||||
Atovaquone | 95233-18-4 | sc-217675 | 10 mg | $270.00 | 2 | |
Inhibits complex III, potentially affecting Grim19 function in the electron transport chain. | ||||||
Paraquat chloride | 1910-42-5 | sc-257968 | 250 mg | $168.00 | 7 | |
Generates reactive oxygen species, potentially disrupting mitochondrial function and indirectly impacting Grim19. | ||||||
Carboxine | 5234-68-4 | sc-234286 | 250 mg | $21.00 | 1 | |
Inhibits succinate dehydrogenase (complex II), potentially affecting Grim19 by disrupting electron transport. | ||||||