Carboxine (CAS 5234-68-4)
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Carboxine is a chemical that functions as a broad-spectrum fungicide. It acts by inhibiting the biosynthesis of sterols in fungal cell membranes, disrupting their structure and function. This disruption leads to the leakage of cellular contents and ultimately the death of the fungal cells. Carboxine′s mechanism of action involves binding to the cytochrome b protein in the mitochondrial respiratory chain of the fungi, interfering with the electron transport process. This disruption impairs the energy production of the fungal cells, leading to their inability to grow and reproduce. Carboxine may have protective effects on plants by preventing the spread of fungal growth, making it useful in agricultural research and development. Its mechanism of action at the molecular level may be a valuable asset in studying fungal biology and developing strategies for crop protection.
Carboxine (CAS 5234-68-4) References
- [Bronchial hyperreactivity in chemical plant workers employed in the production of dust pesticides]. | Kossmann, S., et al. 1999. Wiad Lek. 52: 25-9. PMID: 10335121
- Transformation of Mucor circinelloides with autoreplicative vectors containing homologous and heterologous ARS elements and the dominant Cbx(r) carboxine-resistance gene. | Ortiz-Alvarado, R., et al. 2006. Curr Microbiol. 52: 178-81. PMID: 16502289
- Neutrophil function in chemical plant workers employed in the production of dust pesticides. | Sliwiński, Z., et al. 1991. Pol J Occup Med Environ Health. 4: 241-7. PMID: 1819342
- Two polymorphic forms of the oxathiin systemic fungicide active carboxine. | Frampton, CS., et al. 2018. Acta Crystallogr E Crystallogr Commun. 74: 1741-1745. PMID: 30574366
- A quantitative AOP of mitochondrial toxicity based on data from three cell lines. | Tebby, C., et al. 2022. Toxicol In Vitro. 81: 105345. PMID: 35278637
- [Mechanism of action of the systemic fungicide carboxine]. | Lyr, H., et al. 1972. Z Allg Mikrobiol. 12: 271-80. PMID: 5071608
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Carboxine, 250 mg | sc-234286 | 250 mg | $21.00 |