GRASP55 Inhibitors
Chemical Class Description: The class of GRASP55 inhibitors comprises a diverse range of compounds that indirectly modulate the activity of GRASP55 by targeting various cellular processes and signaling pathways associated with Golgi apparatus function and vesicular trafficking. These compounds do not directly interact with GRASP55 but influence the cellular environment and mechanisms crucial for its function. Brefeldin A, Golgicide A, and Monensin disrupt the structure and function of the Golgi apparatus, thereby potentially affecting the role of GRASP55 in Golgi maintenance and assembly. Nocodazole and Vinblastine, by affecting microtubule dynamics, impact the processes of vesicular trafficking in which GRASP55 is involved.
Tunicamycin and Thapsigargin, targeting protein glycosylation and inducing ER stress respectively, can influence the protein processing and ER-Golgi interactions, thereby affecting GRASP55's activity. PI3K inhibitors like Wortmannin and LY294002, as well as the mTOR inhibitor Rapamycin, modulate signaling pathways that might influence GRASP55 function in Golgi organization and vesicle transport. Dynasore, by inhibiting Dynamin, impacts vesicle trafficking, a key process in GRASP55's function. Cytochalasin D, targeting actin polymerization, affects the cytoskeletal dynamics crucial for vesicular trafficking and thus GRASP55's role
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Disrupts Golgi apparatus structure, potentially affecting GRASP55's role in Golgi maintenance. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Destabilizes microtubules, impacting vesicular trafficking and GRASP55 function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
PI3K inhibitor, could alter signaling pathways involving GRASP55. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Another PI3K inhibitor, potentially affecting pathways linked to GRASP55. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor, may influence processes related to GRASP55 function. | ||||||
Golgicide A | 1005036-73-6 | sc-215103 sc-215103A | 5 mg 25 mg | $191.00 $683.00 | 11 | |
Specifically disrupts Golgi apparatus, indirectly affecting GRASP55's role. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Inhibits Dynamin, impacting vesicle trafficking related to GRASP55. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Ionophore that disrupts Golgi function, potentially impacting GRASP55. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Induces ER stress, can affect Golgi function and GRASP55 activity. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Inhibits actin polymerization, affecting GRASP55's role in vesicular trafficking. | ||||||