GRAMD2 Activators
The chemical activators listed for GRAMD2 are rooted in the protein's interactions within cellular environments. Brefeldin A and Tunicamycin stand out due to their direct impact on the Golgi apparatus and protein glycosylation processes, pointing towards GRAMD2's conceivable relationship with these cellular functions. Further, phosphatidylinositol, a major phospholipid, and related kinase like Wortmannin and LY294002, elucidate the probable connections between lipid signaling and GRAMD2's activities.
Additionally, the highlighted chemicals such as Forskolin and Rapamycin are representative of the cyclic AMP and mTOR pathways, respectively, revealing GRAMD2's expansive ties to diverse cellular communication methods. Protein phosphatase like Calyculin A and Okadaic acid also emphasize the importance of protein post-translational modifications, especially phosphorylation, in GRAMD2's activity. The role of Ionomycin, a calcium ionophore, extends the scope to calcium signaling, highlighting the protein's vast reach in cellular processes.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Influences the Golgi apparatus dynamics, impacting proteins associated with GRAMD2. | ||||||
L-α-Phosphatidylinositol sodium salt | 383907-36-6 | sc-221821 | 10 mg | $408.00 | 1 | |
As a major phospholipid component, PI can affect membrane-associated proteins, including GRAMD2. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
PI3-kinase inhibitor that alters lipid signaling, which can affect GRAMD2's function. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylyl cyclase, increasing cAMP levels which can influence GRAMD2-associated pathways. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Protein phosphatase inhibitor that modulates various signaling pathways, impacting GRAMD2. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $49.00 $57.00 $187.00 | 142 | |
Tyrosine phosphatase inhibitor that can influence signaling pathways connected with GRAMD2. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3-kinase inhibitor that alters lipid signaling pathways that can involve GRAMD2. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Protein phosphatase inhibitor which modulates various signaling processes, impacting GRAMD2. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor, affecting various signaling pathways that can impact GRAMD2-related processes. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits N-linked glycosylation, affecting cellular pathways which can influence GRAMD2. | ||||||