GPR155 Activators
GPR155 activators are primarily focused on indirect activation through the modulation of G protein-coupled receptor pathways. GPCRs are a large family of cell surface receptors that respond to various extracellular signals. The activation of these receptors typically involves the binding of a ligand, which triggers a conformational change in the receptor, leading to the activation of intracellular G proteins. These G proteins then modulate various secondary messengers and signaling pathways within the cell.
Forskolin, for instance, directly stimulates adenylyl cyclase, leading to an increase in cyclic AMP (cAMP) levels, a common secondary messenger involved in GPCR signaling. This increase in cAMP can have downstream effects on various GPCRs, including GPR155. On the other hand, compounds like Isoproterenol and Pilocarpine act as agonists for specific GPCRs (beta-adrenergic and muscarinic acetylcholine receptors, respectively). Their action can influence the overall GPCR landscape within a cell, which may include effects on GPR155 signaling.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin directly activates adenylyl cyclase, increasing cAMP levels, which can modulate GPCR activity including GPR155. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
A non-selective beta-adrenergic agonist, indirectly influencing GPCR signaling, potentially affecting GPR155. | ||||||
Pilocarpine | 92-13-7 | sc-479256 | 100 mg | $250.00 | 1 | |
A muscarinic acetylcholine receptor agonist, affecting GPCR-mediated signaling pathways. | ||||||
Carbachol | 51-83-2 | sc-202092 sc-202092A sc-202092C sc-202092D sc-202092B sc-202092E | 1 g 10 g 25 g 50 g 100 g 250 g | $120.00 $275.00 $380.00 $670.00 $1400.00 $3000.00 | 12 | |
Another muscarinic receptor agonist, it can indirectly influence GPCR activity, including GPR155. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
Acting on adenosine receptors, a type of GPCR, which can modulate other GPCR activities. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
As a neurotransmitter, it acts on dopamine receptors (GPCRs), potentially influencing GPR155 activity through signaling cascades. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Acts on adrenergic receptors (GPCRs), and could indirectly modulate GPR155 activity. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $92.00 $277.00 $969.00 | 7 | |
Targeting histamine receptors (GPCRs), it could have an indirect effect on GPR155. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $291.00 $566.00 | ||
As a major neurotransmitter, it can modulate GPCR signaling indirectly. | ||||||
3-(2-Aminoethyl)-1H-indol-5-ol | 50-67-9 | sc-298707 | 1 g | $520.00 | 3 | |
Targets serotonin receptors, a type of GPCR, potentially affecting GPR155 indirectly. | ||||||