Pilocarpine (CAS 92-13-7)
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Pilocarpine is an alkaloid compound that has garnered attention in the field of biochemistry, particularly for its ability to bind and activate muscarinic acetylcholine receptors. In research applications outside of clinical settings, Pilocarpine is often utilized to study the pharmacology of cholinergic neurotransmission, as well as the physiological responses to muscarinic receptor activation. Investigations may examine the impact of Pilocarpine on secretory functions in exocrine tissues or its effects on smooth muscle contraction in vitro. The compound is also used in research models to induce responses that mimic those of the parasympathetic nervous system, which aids in understanding the underlying mechanisms of neurotransmitter action. Additionally, Pilocarpine may serve as a tool compound in the development of receptor agonists or antagonists by providing a reference point for the design of molecules with similar or opposing activities.
Pilocarpine (CAS 92-13-7) References
- Sites of reaction of pilocarpine. | Satterfield, M. and Brodbelt, JS. 1999. J Am Soc Mass Spectrom. 10: 209-16. PMID: 10069045
- Subnanogram assay for pilocarpine in biological fluids. | Bayne, WF., et al. 1976. J Pharm Sci. 65: 1724-8. PMID: 1032652
- Pump infusion of pilocarpine. | Harris, LS. and Kahanowicz, Y. 1975. Ophthalmologica. 171: 157-64. PMID: 1153174
- Pilocarpine dispensation for the soft hydrophilic contact lens. | Ruben, M. and Watkins, R. 1975. Br J Ophthalmol. 59: 455-8. PMID: 1203231
- Simultaneous determination of pilocarpine and isopilocarpine in pharmaceutical preparations by liquid chromatography. | Urbányi, T., et al. 1976. J Pharm Sci. 65: 257-60. PMID: 1255459
- Salivary flow induction by buccal permucosal pilocarpine in anesthetized beagle dogs. | Weaver, ML., et al. 1992. J Dent Res. 71: 1762-7. PMID: 1401437
- Unraveling the biosynthesis of pilocarpine in Pilocarpus microphyllus. | Sawaya, AC., et al. 2015. Nat Prod Commun. 10: 721-4. PMID: 26058143
- Compliance with topical pilocarpine treatment. | Kass, MA., et al. 1986. Am J Ophthalmol. 101: 515-23. PMID: 3706455
- Pilocarpine used to stimulate normal saliva production. | . 1985. J Am Dent Assoc. 111: 310. PMID: 3862698
- Pilocarpine prodrugs I. Synthesis, physicochemical properties and kinetics of lactonization of pilocarpic acid esters. | Bundgaard, H., et al. 1986. J Pharm Sci. 75: 36-43. PMID: 3958903
- Corneal metabolism of pilocarpine in pigmented rabbits. | Lee, VH., et al. 1980. Invest Ophthalmol Vis Sci. 19: 210-3. PMID: 7351355
- Pilocarpine incorporated into a submicron emulsion vehicle causes an unexpectedly prolonged ocular hypotensive effect in rabbits. | Naveh, N., et al. 1994. J Ocul Pharmacol. 10: 509-20. PMID: 7836859
- Effect of pilocarpine on anterior chamber angles. | Hung, L., et al. 1995. J Ocul Pharmacol Ther. 11: 221-6. PMID: 8590253
- Pilocarpine ocular inserts. | Bensinger, R., et al. 1976. Invest Ophthalmol. 15: 1008-10. PMID: 992960
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pilocarpine, 100 mg | sc-479256 | 100 mg | $255.00 |