GPR139 Activators
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
TC-O 9311 | 444932-31-4 | sc-362802 sc-362802A | 10 mg 50 mg | $116.00 $620.00 | ||
TC-O 9311 functions as a selective GPR139 agonist, exhibiting a unique binding affinity that stabilizes the receptor in an active conformation. This compound's specific molecular interactions promote the activation of downstream signaling pathways, influencing neuronal activity and metabolic processes. Its distinct structural features enhance receptor selectivity, while its kinetic profile suggests rapid engagement and dissociation, allowing for precise modulation of receptor-mediated responses. | ||||||
L-Phenylalanine | 63-91-2 | sc-394058 sc-394058A sc-394058B | 100 g 500 g 1 kg | $114.00 $466.00 $693.00 | 1 | |
An essential amino acid that serves as a direct ligand for GPR139. Its binding to the receptor activates associated G protein signaling pathways, leading to downstream cellular responses. | ||||||
L-Tryptophan | 73-22-3 | sc-280888 sc-280888A sc-280888B | 100 g 1 kg 5 kg | $129.00 $364.00 $1795.00 | ||
Another direct ligand for GPR139. Its binding modulates the receptor's activity and influences neurochemical pathways, particularly those involving serotonin synthesis. | ||||||
Calcium D-gluconate | 299-28-5 | sc-221393 sc-221393A | 100 g 500 g | $40.00 $145.00 | ||
A calcium salt influencing intracellular calcium levels, thereby modulating GPCR activity including GPR139 through calcium-dependent signaling mechanisms. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An activator of adenylate cyclase, enhances cAMP levels, which in turn can modulate GPCR activity, including GPR139, via cAMP-dependent protein kinase (PKA) pathways. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid that influences various signaling pathways, including those involving kinases and phosphatases, potentially impacting GPR139 signaling indirectly. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor, modulates cellular signaling pathways including those linked to GPCRs, which could affect GPR139 function. | ||||||
Dextromethorphan | 125-71-3 | sc-278927 sc-278927A sc-278927B | 10 g 100 g 500 g | $177.00 $1156.00 $5208.00 | 3 | |
Known for NMDA receptor antagonism, also modulates sigma-1 receptors, influencing intracellular signaling pathways that could indirectly affect GPR139 activity. | ||||||
Diazoxide | 364-98-7 | sc-200980 | 1 g | $300.00 | 5 | |
Opens ATP-sensitive potassium channels, influencing cellular excitability and indirectly modulating GPCR activity, including GPR139. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
A beta-adrenergic antagonist, influences GPCR-mediated pathways, potentially affecting GPR139 signaling in a secondary manner. | ||||||