Dextromethorphan (CAS 125-71-3)
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Dextromethorphan is frequently explored in neuroscience research for its unique effects on brain chemistry, particularly its role as an NMDA receptor antagonist. Scientists are interested in how dextromethorphan modulates neural activity, which can provide insights into the mechanisms of neural protection and the prevention of nerve cell damage due to overstimulation. This compound is also useful in studies aiming to understand the complex neural pathways involved in the cough reflex, making it a subject of interest beyond its well-known application. In addition, dextromethorphan is used to examine the interactions of neurotransmitters and receptors within the brain, shedding light on the broader implications for brain health and function. Moreover, its interaction with sigma-1 receptors adds another layer of interest, as this may influence a range of neural processes.
Dextromethorphan (CAS 125-71-3) References
- Dextromethorphan and diabetic neuropathy. | Criner, TM. and Perdun, CS. 1999. Ann Pharmacother. 33: 1221-3. PMID: 10573324
- Dextromethorphan abuse. | Boyer, EW. 2004. Pediatr Emerg Care. 20: 858-63. PMID: 15572980
- Dextromethorphan/quinidine: a novel dextromethorphan product for the treatment of emotional lability. | Smith, RA. 2006. Expert Opin Pharmacother. 7: 2581-98. PMID: 17150011
- Dextromethorphan: a review of N-methyl-d-aspartate receptor antagonist in the management of pain. | Siu, A. and Drachtman, R. 2007. CNS Drug Rev. 13: 96-106. PMID: 17461892
- Neuropsychotoxic and neuroprotective potentials of dextromethorphan and its analogs. | Shin, EJ., et al. 2011. J Pharmacol Sci. 116: 137-48. PMID: 21606622
- Dextromethorphan and sigma ligands: common sites but diverse effects. | Musacchio, JM., et al. 1989. Life Sci. 45: 1721-32. PMID: 2556614
- Dextromethorphan and neuromodulation: old drug coughs up new activities. | Tortella, FC., et al. 1989. Trends Pharmacol Sci. 10: 501-7. PMID: 2694543
- Dextromethorphan in Cough Syrup: The Poor Man's Psychosis. | Martinak, B., et al. 2017. Psychopharmacol Bull. 47: 59-63. PMID: 28936010
- Interventional Study of Dextromethorphan Abuse Within the U.S. Military Community in Okinawa, Japan. | Armstrong, C. and Kapolowicz, MR. 2020. Mil Med. 185: e926-e929. PMID: 32236409
- Efficacy of dextromethorphan for the treatment of depression: a systematic review of preclinical and clinical trials. | Majeed, A., et al. 2021. Expert Opin Emerg Drugs. 26: 63-74. PMID: 33682569
- The regioselectivity of the interaction between dextromethorphan and CYP2D6. | Sun, MZ. and Zheng, QC. 2022. Phys Chem Chem Phys. 24: 2234-2242. PMID: 35014636
- Dextromethorphan: From Cough Suppressant to Antidepressant. | Kverno, K. 2022. J Psychosoc Nurs Ment Health Serv. 60: 9-11. PMID: 36317836
- Combinations of dextromethorphan for the treatment of mood disorders - a review of the evidence. | Parincu, Z. and Iosifescu, DV. 2023. Expert Rev Neurother. 23: 205-212. PMID: 36943010
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dextromethorphan, 10 g | sc-278927 | 10 g | $177.00 | |||
Dextromethorphan, 100 g | sc-278927A | 100 g | $1156.00 | |||
Dextromethorphan, 500 g | sc-278927B | 500 g | $5208.00 |