GnT-III Activators
The category of GnT-III activators primarily encompasses chemicals central to the glycosylation pathways and the broader metabolism. Among these, UDP-GlcNAc stands out as a pivotal player, acting as a direct substrate for MGAT3 and underpinning its glycosyltransferase function. This importance of UDP-GlcNAc is also echoed in the actions of Glucose, Glucosamine, and GlcNAc. These compounds either boost cellular levels of UDP-GlcNAc or serve as precursors in its synthesis, reinforcing their capacity to stimulate MGAT3.
Complementing these chemicals, other activators function by modulating the expression or operational dynamics of MGAT3. Substances like cAMP and Forskolin interact with cellular pathways, potentially amplifying MGAT3's expression or activity. Similarly, Insulin, renowned for its role in metabolic regulation, can influence the glycosylation processes which MGAT3 is part of. Growth factors like EGF have the capability to promote pathways culminating in escalated MGAT3 expression in specific cellular contexts.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D(+)Glucose, Anhydrous | 50-99-7 | sc-211203 sc-211203B sc-211203A | 250 g 5 kg 1 kg | $38.00 $198.00 $65.00 | 5 | |
Increases UDP-GlcNAc pools which in turn can stimulate MGAT3 activity. | ||||||
D-Glucosamine | 3416-24-8 | sc-278917A sc-278917 | 1 g 10 g | $201.00 $779.00 | ||
Boosts the cellular levels of UDP-GlcNAc, potentially enhancing MGAT3 functionality. | ||||||
N-Acetyl-D-glucosamine | 7512-17-6 | sc-286377 sc-286377B sc-286377A | 50 g 100 g 250 g | $94.00 $162.00 $306.00 | 1 | |
Serves as a direct substrate for MGAT3, essential for its glycosyltransferase activity. | ||||||
D-Mannose | 3458-28-4 | sc-211180 sc-211180A | 100 g 250 g | $103.00 $161.00 | 1 | |
Elevates cellular levels of GDP-Man, which indirectly can influence MGAT3 substrate availability. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Can modulate pathways enhancing the expression and activity of MGAT3. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Regulates metabolic pathways and glycosylation processes, potentially affecting MGAT3 function. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Known to induce MGAT3 expression in some cell types, potentially influencing its activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, elevating cAMP levels, which can indirectly influence MGAT3 pathways. | ||||||