D-Mannose (CAS 3458-28-4)
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D-Mannose is a monosaccharide that is widely used in research involving carbohydrate metabolism and glycosylation processes. In studies of bacterial adhesion, D-Mannose is particularly valuable as it interferes with the attachment of certain pathogens to host cells, enabling the investigation of infection mechanisms and host-pathogen interactions. It is also employed in the study of the mannose-specific lectin pathway, part of the immune system′s response to pathogens. D-Mannose is utilized in the synthesis of glycoconjugates for research into cell signaling and intercellular communication, as mannose-containing oligosaccharides play a role in these biological processes. Furthermore, it serves as a tool in the analysis of protein glycosylation patterns, contributing to the understanding of protein structure-function relationships.
D-Mannose (CAS 3458-28-4) References
- D-mannose: a promising support for acute urinary tract infections in women. A pilot study. | Domenici, L., et al. 2016. Eur Rev Med Pharmacol Sci. 20: 2920-5. PMID: 27424995
- Role of D-Mannose in the Prevention of Recurrent Urinary Tract Infections: Evidence from a Systematic Review of the Literature. | Kyriakides, R., et al. 2021. Eur Urol Focus. 7: 1166-1169. PMID: 32972899
- D-mannose suppresses macrophage IL-1β production. | Torretta, S., et al. 2020. Nat Commun. 11: 6343. PMID: 33311467
- D-mannose ameliorates autoimmune phenotypes in mouse models of lupus. | Wang, H., et al. 2021. BMC Immunol. 22: 1. PMID: 33402096
- D-mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF-2α-dependent manner. | Zhou, X., et al. 2021. Cell Prolif. 54: e13134. PMID: 34561933
- d-mannose suppresses oxidative response and blocks phagocytosis in experimental neuroinflammation. | Wang, J., et al. 2021. Proc Natl Acad Sci U S A. 118: PMID: 34702739
- D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1. | Zhang, R., et al. 2022. Proc Natl Acad Sci U S A. 119: PMID: 35181605
- Role of D-mannose in urinary tract infections - a narrative review. | Ala-Jaakkola, R., et al. 2022. Nutr J. 21: 18. PMID: 35313893
- d-mannose administration improves autoimmune hepatitis by upregulating regulatory T cells. | Ito, D., et al. 2022. Cell Immunol. 375: 104517. PMID: 35398604
- Non-antibiotic Approaches to Preventing Pediatric UTIs: a Role for D-Mannose, Cranberry, and Probiotics? | Ching, CB. 2022. Curr Urol Rep. 23: 113-127. PMID: 35441976
- D-Mannose Regulates Hepatocyte Lipid Metabolism via PI3K/Akt/mTOR Signaling Pathway and Ameliorates Hepatic Steatosis in Alcoholic Liver Disease. | Hu, M., et al. 2022. Front Immunol. 13: 877650. PMID: 35464439
- D-mannose for preventing and treating urinary tract infections. | Cooper, TE., et al. 2022. Cochrane Database Syst Rev. 8: CD013608. PMID: 36041061
- D-Mannose prevents bone loss under weightlessness. | Gu, R., et al. 2023. J Transl Med. 21: 8. PMID: 36617569
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Mannose, 100 g | sc-211180 | 100 g | $101.00 | |||
D-Mannose, 250 g | sc-211180A | 250 g | $158.00 |