Gm885 Activators
Mast cell immunoglobulin-like receptor 1 activators are a class of compounds that influence cellular processes and signal transduction pathways, leading to the enhancement of the functional activity of mast cell immunoglobulin-like receptor 1. These activators work through various intracellular signaling cascades that are fundamental to cell communication and response mechanisms. For instance, compounds such as forskolin and isoproterenol raise intracellular cyclic AMP (cAMP) levels. The increased cAMP activates protein kinase A (PKA), which can phosphorylate numerous substrates within the cell, thereby amplifying the signaling pathways that mast cell immunoglobulin-like receptor 1 is involved in. Similarly, ionomycin and A23187 function as calcium ionophores, increasing intracellular calcium concentration and potentially activating calcium-dependent kinases, which may phosphorylate and enhance the activity of mast cell immunoglobulin-like receptor 1.
On the other hand, compounds that inhibit the breakdown of cAMP, such as rolipram and IBMX, maintain elevated levels of cAMP within the cell, further stimulating PKA activity and enhancing the phosphorylation state of proteins that could be associated with mast cell immunoglobulin-like receptor 1 signaling.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Adenylyl cyclase activator that increases intracellular cAMP levels, thereby activating PKA. The activation of PKA can lead to phosphorylation events that enhance the signaling capacity of mast cell immunoglobulin-like receptor 1. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Calcium ionophore that increases intracellular Ca2+ concentration, potentially activating Ca2+-dependent kinases which may enhance the phosphorylation and activity of mast cell immunoglobulin-like receptor 1. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activator of protein kinase C (PKC) which can phosphorylate target proteins, potentially enhancing the signaling processes involving mast cell immunoglobulin-like receptor 1. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
cAMP analog that activates PKA, potentially enhancing the phosphorylation state of proteins associated with mast cell immunoglobulin-like receptor 1 signaling. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
Calcium ionophore similar to ionomycin, it raises intracellular Ca2+ levels and can activate signaling pathways that enhance the activity of mast cell immunoglobulin-like receptor 1. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Inhibitor of serine/threonine protein phosphatases PP1 and PP2A, leading to increased phosphorylation levels within cells, which could enhance the functional activity of mast cell immunoglobulin-like receptor 1. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
Beta-adrenergic agonist that can lead to increased levels of cAMP and activate PKA, potentially enhancing the signaling processes of mast cell immunoglobulin-like receptor 1. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Tyrosine kinase inhibitor that, by influencing tyrosine kinase activity, could affect phosphorylation patterns relevant for the activation of mast cell immunoglobulin-like receptor 1. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Phosphodiesterase-4 inhibitor that prevents cAMP breakdown, potentially increasing PKA activity and enhancing the functional activity of mast cell immunoglobulin-like receptor 1. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Non-selective phosphodiesterase inhibitor that increases cAMP levels by preventing its breakdown, potentially enhancing PKA-mediated signaling relevant to mast cell immunoglobulin-like receptor 1. | ||||||