Gm22 Activators
Zinc finger protein 469 activators encompass a range of chemical compounds that, through various pathways and molecular interactions, lead to enhanced functional activity of the zinc finger protein 469. Bisphenol A, known for its ability to mimic estrogen, binds to estrogen receptors and facilitates the transcription of estrogen-responsive genes, which could encompass zinc finger protein 469 if it possesses estrogen response elements. Retinoic acid, through its interaction with retinoic acid receptors, modulates gene expression, including the potential upregulation of zinc finger proteins. Dibutyryl-cAMP, a cAMP analog, and Forskolin, which increases intracellular cAMP levels, both activate protein kinase A, possibly enhancing the transcription of genes including zinc finger protein 469 through phosphorylation of transcription factors.
Compounds such as Phorbol 12-myristate 13-acetate activate protein kinase C, which influences transcription factors and could increase the expression of zinc finger protein 469. Histone deacetylase inhibitors like Trichostatin A and Sodium butyrate, as well as DNA methylation inhibitors such as 5-Azacytidine and Epigallocatechin gallate, induce epigenetic modifications that can lead to an increase in gene expression, including that of zinc finger protein 469. Lithium chloride's inhibition of glycogen synthase kinase-3 could enhance the transcription of target genes. Curcumin's modulation of transcription factors and signaling pathways could lead to the upregulation of zinc finger proteins, and Resveratrol's activation of sirtuin 1 may similarly influence the expression profile of genes including zinc finger protein 469.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Bisphenol A binds to estrogen receptor sites, potentially increasing the expression of estrogen-responsive genes, including zinc finger protein 469, which may be upregulated due to its estrogen response element. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid acts on retinoic acid receptors, which can heterodimerize with other nuclear receptors influencing the transcription of genes including those coding for zinc finger proteins like zinc finger protein 469. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Dibutyryl-cAMP, a cAMP analog, activates protein kinase A, which can phosphorylate transcription factors that enhance expression of genes, including possibly zinc finger protein 469. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels and subsequently activating PKA, which could enhance the transcription of proteins including zinc finger protein 469. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C which can modulate transcription factors and gene expression profiles, potentially increasing the expression of zinc finger protein 469. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is an inhibitor of histone deacetylases, which can lead to a more accessible chromatin structure and the potential upregulation of genes including zinc finger protein 469. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methylation inhibitor, which could lead to the demethylation and activation of gene promoters, potentially enhancing the expression of genes like zinc finger protein 469. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate is a histone deacetylase inhibitor, which may result in a more relaxed chromatin structure and possible upregulation of specific genes, such as zinc finger protein 469. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG can inhibit DNA methyltransferases, possibly leading to hypomethylation of gene promoters and upregulation of certain genes, including zinc finger protein 469. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can inhibit glycogen synthase kinase-3, potentially altering the phosphorylation state of transcription factors and enhancing the transcription of genes like zinc finger protein 469. | ||||||