Glyoxalase I Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Glutathione, reduced | 70-18-8 | sc-29094 sc-29094A | 10 g 1 kg | $76.00 $2050.00 | 8 | |
Glutathione, in its reduced form, plays a crucial role as a glyoxalase I cofactor, facilitating the detoxification of reactive carbonyl species. It engages in nucleophilic attack on glyoxal, forming a thiohemiacetal intermediate that stabilizes the reaction. This process enhances the enzyme's efficiency, promoting rapid conversion of toxic metabolites. Additionally, its tripeptide structure allows for versatile interactions with various substrates, influencing cellular redox states and metabolic pathways. | ||||||
S-Ethylglutathione | 24425-52-3 | sc-208327 | 10 mg | $330.00 | ||
S-Ethylglutathione serves as a potent cofactor for glyoxalase I, participating in the detoxification of harmful carbonyl compounds. Its ethyl group enhances hydrophobic interactions, promoting substrate binding and stabilizing transition states during enzymatic reactions. This modification can influence the kinetics of the glyoxalase pathway, allowing for more efficient processing of reactive metabolites. The compound's unique structure also facilitates interactions with other cellular components, impacting overall metabolic regulation. | ||||||
Methylglyoxal solution | 78-98-8 | sc-250394 sc-250394A sc-250394B sc-250394C sc-250394D | 25 ml 100 ml 250 ml 500 ml 1 L | $143.00 $428.00 $469.00 $739.00 $1418.00 | 3 | |
As a substrate of Glyoxalase I, excessive levels of Methylglyoxal may lead to enzyme saturation and inhibition, impacting its expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has demonstrated potential in modulating various cellular pathways, possibly leading to the downregulation of Glyoxalase I expression. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Disulfiram is known to interact with multiple enzymes, and it may inhibit Glyoxalase I expression as part of its broader effects on cellular function. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has been shown to influence gene expression and may modulate the levels of Glyoxalase I indirectly through its effects on signaling pathways. | ||||||
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $60.00 $75.00 $125.00 $205.00 | 8 | |
Sulfasalazine has anti-inflammatory effects and may influence the expression of various enzymes, including Glyoxalase I, as part of its action. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $106.00 $765.00 | 3 | |
Exposure to arsenic compounds like Sodium (meta)arsenite can disrupt cellular processes and potentially lead to the downregulation of Glyoxalase I. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $55.00 $179.00 $345.00 | 1 | |
Cadmium exposure is known to induce oxidative stress and may affect the expression of enzymes involved in detoxification, such as Glyoxalase I. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin has antioxidant properties and has been shown to influence the expression of various genes, potentially impacting Glyoxalase I levels. | ||||||