GHITM, or Growth Hormone Inducible Transmembrane Protein, is a protein whose function and importance in cellular processes have garnered interest in the scientific community. It is a transmembrane protein, meaning it spans the lipid bilayer of cells, typically allowing it to play roles in various cellular activities such as signaling, transport, or anchoring. The presence of the term "growth hormone inducible" in its name suggests its expression or function may be influenced by growth hormones, which are crucial regulators of various physiological processes including growth, metabolism, and development.
Inhibitors targeting GHITM aim to modulate its activity or expression. The rationale behind developing GHITM inhibitors can be diverse, depending on the specific cellular processes or pathways in which GHITM is involved. For instance, if GHITM facilitates a particular cellular signal transduction pathway, an inhibitor could be designed to prevent this, thereby modulating the outcome of that signaling pathway. The design of GHITM inhibitors requires an intricate understanding of the protein's structure and function. In-depth studies on GHITM's interactions, its conformational changes, and its binding sites can offer insights that guide the design of effective inhibitors. Additionally, it's essential to consider the broader cellular context. Since GHITM is a transmembrane protein, its interaction with the lipid bilayer and other adjacent proteins can influence its function and, consequently, the design and function of potential inhibitors. The exploration into GHITM inhibitors exemplifies the complexities and opportunities in targeting specific proteins to modulate cellular processes, highlighting the intricate interplay of molecular interactions that define cellular function.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
An antimetabolite that inhibits DNA synthesis, potentially reducing GHITM expression indirectly. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that might modify chromatin structure and affect GHITM expression. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $256.00 | 18 | |
An estrogen receptor modulator that could have off-target effects on other gene expressions, including GHITM. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A compound affecting cellular differentiation, which might indirectly modulate GHITM expression. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Inhibits ribonucleotide reductase, potentially affecting DNA synthesis and indirectly GHITM expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A tyrosine kinase inhibitor that might affect signaling pathways indirectly influencing GHITM expression. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
An Hsp90 inhibitor that can affect multiple proteins and might indirectly modulate GHITM stability or expression. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
An inhibitor of protein synthesis, which could decrease GHITM protein levels. | ||||||
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $67.00 $306.00 | 2 | |
A cyclin-dependent kinase inhibitor that might affect cell cycle progression and potentially GHITM expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that might modulate signaling pathways and indirectly affect GHITM expression. | ||||||