Ggnbp2 Inhibitors

Chemicals classified as Ggnbp2 inhibitors would encompass a range of compounds that, through their action on various cellular processes, can indirectly modulate the activity of Ggnbp2. The listed chemicals affect pathways such as DNA replication, repair, cell cycle progression, and cell survival. For instance, inhibitors like Aphidicolin, Camptothecin, and Etoposide target enzymes critical for DNA replication and repair, which are processes where Ggnbp2 may play a role. Consequently, these inhibitors can alter the function and possibly the regulation of Ggnbp2.

Further, ATM and DNA-PKcs are essential kinases in the response to DNA damage, and their inhibition by KU-55933 and NU7441, respectively, can impact signaling cascades that possibly involve Ggnbp2. PARP, ATR, and CHK1 are other targets within the DNA damage response pathway, and inhibitors such as Olaparib, VE-821, and AZD7762 can affect the recruitment or function of proteins involved in this pathway, including potentially Ggnbp2. PI3K inhibitors like PI-103, Wortmannin, and LY294002, as well as the protein kinase C inhibitor UCN-01, can disrupt signaling pathways that regulate cell growth and survival, which may have consequences for proteins that are implicated in these processes, such as Ggnbp2.