Date published: 2026-5-6

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 101 to 110 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2-[2-(2-t-Boc-aminoethoxy)ethoxy]ethanol

139115-92-7sc-208968
250 mg
$305.00
(1)

2-[2-(2-t-Boc-aminoethoxy)ethoxy]ethanol serves as an effective crosslinker due to its multifunctional structure, which enables robust interactions with polymer chains. The t-Boc group provides steric hindrance, influencing reaction kinetics and enhancing stability during crosslinking processes. Its ether linkages facilitate solubility in various solvents, promoting compatibility with diverse materials. This compound's ability to form dynamic covalent bonds allows for tailored network formation, optimizing mechanical properties in polymer matrices.

DPDPB

141647-62-3sc-237746
10 mg
$134.00
(0)

DPDPB functions as an effective crosslinker, characterized by its ability to form robust covalent bonds through its unique reactivity with functional groups. Its distinct molecular structure facilitates the formation of crosslinked networks, enhancing mechanical stability and durability. The compound exhibits a favorable reaction profile, promoting efficient crosslinking under mild conditions. Additionally, its versatility allows for tailored modifications, enabling the design of customized materials with specific properties.

4,4′-Diisothiocyano-2,2′-dihydrostilbenedisulfonic Acid Disodium Salt

150321-88-3sc-281687
250 mg
$349.00
(0)

4,4'-Diisothiocyano-2,2'-dihydrostilbenedisulfonic Acid Disodium Salt serves as an effective crosslinker due to its unique isothiocyanate groups, which facilitate strong covalent bonding with nucleophilic sites in polymers. This compound promotes enhanced network formation, improving mechanical strength and thermal stability. Its dual sulfonic acid groups contribute to increased solubility in aqueous environments, allowing for efficient dispersion and reaction kinetics in polymerization processes.

6-Maleimidocaproic Acid Hydrazide, Trifluoroacetic Acid

151038-94-7sc-210528
50 mg
$245.00
(0)

6-Maleimidocaproic Acid Hydrazide, Trifluoroacetic Acid acts as an effective crosslinker, distinguished by its hydrazide functionality that enables robust conjugation with carbonyl-containing compounds. The trifluoroacetic acid moiety enhances solubility and stability, while the maleimide group facilitates selective thiol reactions, promoting precise crosslinking in diverse environments. This compound's unique reactivity profile allows for the formation of intricate networks, optimizing structural integrity and functionality.

4-(Bromomethyl)phenyl isothiocyanate

155863-32-4sc-226400
1 g
$189.00
(0)

4-(Bromomethyl)phenyl isothiocyanate serves as a versatile crosslinker, characterized by its ability to engage in thiourea formation through nucleophilic attack. The presence of the isothiocyanate group enables selective reactivity with nucleophiles, facilitating the creation of robust polymer networks. Its unique molecular configuration allows for diverse crosslinking strategies, while the bromomethyl moiety enhances reactivity, promoting efficient and tailored polymerization processes.

3-(Fmoc-amino)-1-propanol

157887-82-6sc-238466
1 g
$67.00
(0)

3-(Fmoc-amino)-1-propanol serves as a versatile crosslinker, characterized by its capacity to engage in robust hydrogen bonding and hydrophobic interactions. The Fmoc moiety not only protects the amine but also enhances the compound's solubility in various organic media. Its propanol backbone introduces a degree of steric hindrance, influencing reaction kinetics and enabling precise control over polymer network formation. This compound's unique structural features allow for the customization of material properties, such as elasticity and thermal behavior.

Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate

158913-22-5sc-212962
10 mg
$190.00
(0)

Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate is a specialized crosslinker known for its ability to form covalent bonds through thiol-disulfide exchange reactions. This compound features a pyridyldithio moiety that selectively reacts with thiol groups, enabling the formation of stable linkages between biomolecules. Its unique structure allows for controlled crosslinking, enhancing the stability and functionality of conjugated systems. The compound's hydrophilic nature ensures compatibility with various biological environments, promoting effective interactions.

Fmoc-Photo-Linker

162827-98-7sc-294977
sc-294977A
sc-294977B
100 mg
1 g
5 g
$269.00
$662.00
$1641.00
6
(0)

Fmoc-Photo-Linker is a versatile crosslinker characterized by its photoreactive properties, enabling precise spatial control over polymer networks. Upon exposure to light, it undergoes a rapid transformation, facilitating the formation of covalent bonds with nearby nucleophiles. This light-triggered reactivity allows for dynamic manipulation of material properties, enhancing the tunability of crosslinked structures. Its compatibility with various solvents further supports its integration into diverse chemical environments, promoting innovative applications in polymer chemistry.

2-[2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid Methyl Ester

165963-73-5sc-208970
5 mg
$360.00
(0)

2-[2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid Methyl Ester serves as an innovative crosslinker, distinguished by its trifluoromethyl and diazirine groups that enhance photoreactivity and facilitate covalent bonding under UV light. The ester functionality promotes efficient esterification reactions, while the ether linkages provide enhanced solubility and compatibility with diverse polymer matrices, enabling tailored material properties and improved structural integrity.

ANP-Linker

171778-06-6sc-291904
sc-291904A
100 mg
5 g
$163.00
$856.00
(0)

ANP-Linker is a specialized crosslinker known for its unique reactivity as an acid halide, which facilitates the formation of stable covalent bonds through nucleophilic substitution. Its distinct molecular structure promotes selective interactions with amines and alcohols, leading to tailored crosslinking pathways. The linker exhibits rapid reaction kinetics, allowing for efficient network formation, while its solubility in various organic solvents enhances its versatility in diverse chemical systems.