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4,4′-Diisothiocyano-2,2′-dihydrostilbenedisulfonic Acid Disodium Salt (CAS 150321-88-3)

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Alternate Names:
2,2'-(1,2-Ethanediyl)bis[5-isothiocyanatobenzenesulfonic Acid Disodium Salt
CAS Number:
150321-88-3
Purity:
98%
Molecular Weight:
500.50
Molecular Formula:
C16H10Na2N2O6S4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A CD4 antagonist that blocks HIV type-1 growth at multiple stages of the virus life cycle. An anion-transport inhibitor that crosslinks hemoglobin interdimerically and enhances oxygen unloading.


4,4′-Diisothiocyano-2,2′-dihydrostilbenedisulfonic Acid Disodium Salt (CAS 150321-88-3) References

  1. Kinetics of DIDS inhibition of swelling-activated K-Cl cotransport in low K sheep erythrocytes.  |  Delpire, E. and Lauf, PK. 1992. J Membr Biol. 126: 89-96. PMID: 1593613
  2. Identification of the eosinyl-5-maleimide reaction site on the human erythrocyte anion-exchange protein: overlap with the reaction sites of other chemical probes.  |  Cobb, CE. and Beth, AH. 1990. Biochemistry. 29: 8283-90. PMID: 1701324
  3. Reversible and irreversible inhibition, by stilbenedisulphonates, of lactate transport into rat erythrocytes. Identification of some new high-affinity inhibitors.  |  Poole, RC. and Halestrap, AP. 1991. Biochem J. 275 (Pt 2): 307-12. PMID: 2025218
  4. Stilbene disulfonic acids. CD4 antagonists that block human immunodeficiency virus type-1 growth at multiple stages of the virus life cycle.  |  Cardin, AD., et al. 1991. J Biol Chem. 266: 13355-63. PMID: 2071607
  5. Electrophysiological properties of anion exchangers in the luminal membrane of guinea pig pancreatic duct cells.  |  Andharia, N., et al. 2018. Pflugers Arch. 470: 897-907. PMID: 29399744

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,4'-Diisothiocyano-2,2'-dihydrostilbenedisulfonic Acid Disodium Salt, 250 mg

sc-281687
250 mg
$342.00