![Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate (CAS 158913-22-5) - chemical structure image](https://media.scbt.com/product/succinimidyl-6-3-2-pyridyldithio-propionamidohexanoate-158913-22-5-structure_09_59_b_95995.jpg)
![Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate (CAS 158913-22-5) - chemical structure image](https://media.scbt.com/product/succinimidyl-6-3-2-pyridyldithio-propionamidohexanoate-158913-22-5-structure_09_59_t_95995.jpg "Molecular structure of Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate, CAS Number: 158913-22-5")
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate (CAS 158913-22-5)
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Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate is a crosslinking agent that is frequently utilized in biochemical and protein chemistry research. This compound is often used to conjugate cysteine-containing peptides or proteins to various molecules, including other proteins or surface materials, due to its reactive functional groups. The pyridyldithio group in Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate is particularly useful in forming disulfide bridges, which can be cleaved under reducing conditions, making it valuable for studies requiring reversible crosslinking. Researchers also employ this reagent in the study of protein structure and function, as it helps in mapping sites of protein interactions and in creating stable protein conjugates for analytical purposes.
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate (CAS 158913-22-5) References
- Anti-EpCAM modified LC-SPDP monolayer on gold microelectrode based electrochemical biosensor for MCF-7 cells detection. | Arya, SK., et al. 2013. Biosens Bioelectron. 41: 446-51. PMID: 23021854
- Multifunctional 'smart' particles engineered from live immunocytes: toward capture and release of cancer cells. | Huang, C., et al. 2015. Adv Mater. 27: 310-3. PMID: 25382706
- Intracellular Cleavable CpG Oligodeoxynucleotide-Antigen Conjugate Enhances Anti-tumor Immunity. | Kramer, K., et al. 2017. Mol Ther. 25: 62-70. PMID: 28129129
- Data on the uptake of reducible antigen-adjuvant conjugates by dendritic cells. | Kramer, K., et al. 2019. Data Brief. 23: 103759. PMID: 31372420
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate, 10 mg | sc-212962 | 10 mg | $190.00 |