Date published: 2026-2-3

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 91 to 100 of 344 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester)

70539-42-3sc-252807
sc-252807A
250 mg
1 g
$129.00
$406.00
2
(0)

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) serves as an effective crosslinker, facilitating the formation of robust polymer networks through its reactive ester groups. These groups engage in dynamic covalent bonding, enhancing mechanical strength and thermal stability in materials. The compound's unique ability to create multi-functional linkages allows for tailored properties in various formulations, while its controlled reaction kinetics enable precise manipulation of crosslink density, optimizing performance in diverse applications.

3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-amine

72236-26-1sc-206715
sc-206715A
sc-206715B
50 mg
250 mg
1 g
$360.00
$510.00
$1000.00
(0)

3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-amine functions as an effective crosslinker, distinguished by its ability to engage in hydrogen bonding and ionic interactions, which enhance network stability. The presence of multiple amine groups facilitates rapid reaction kinetics, enabling efficient crosslinking in diverse polymer systems. Its unique structure promotes compatibility with various substrates, leading to improved mechanical strength and thermal resistance in the final materials.

4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimide ester

79886-55-8sc-252087
25 mg
$112.00
(0)

4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimide ester functions as a versatile crosslinker, characterized by its ability to form stable covalent bonds with thiol groups in proteins and peptides. The maleimide moiety enables selective conjugation, while the N-hydroxysuccinimide group enhances reactivity and stability in aqueous conditions. This compound exhibits rapid reaction kinetics, facilitating efficient crosslinking in various biochemical applications, thereby promoting structural integrity and functional interactions.

4-Maleimidobutyric Acid N-Succinimidyl Ester

80307-12-6sc-210101
100 mg
$297.00
(0)

4-Maleimidobutyric Acid N-Succinimidyl Ester serves as a potent crosslinker, characterized by its ability to form stable amide bonds through reaction with primary amines. This compound features a flexible linker that facilitates spatial arrangement, promoting effective molecular interactions. Its reactivity is enhanced by the presence of the maleimide group, allowing for selective targeting in complex biomolecular environments, thus enabling tailored network formation with specific structural properties.

4-(N-Succinimidylcarboxy)benzophenone

91990-88-4sc-209864
25 mg
$317.00
(0)

4-(N-Succinimidylcarboxy)benzophenone serves as an effective crosslinker, distinguished by its ability to form stable amide bonds through its reactive succinimidyl group. This compound exhibits selective reactivity towards primary amines, enabling precise conjugation in complex biomolecular environments. Its unique photoreactive properties allow for light-mediated crosslinking, enhancing spatial specificity. The resulting polymer networks demonstrate improved mechanical integrity and tailored functionalization, making it a powerful tool in material development.

1,11-Diazido-3,6,9-trioxaundecane

101187-39-7sc-208716
1 g
$525.00
(0)

1,11-Diazido-3,6,9-trioxaundecane functions as a versatile crosslinker, characterized by its azide groups that enable efficient click chemistry reactions. This compound exhibits a high degree of specificity in forming covalent bonds, allowing for precise control over network architecture. Its unique trioxaundecane backbone contributes to enhanced solubility and reactivity, facilitating the development of materials with improved elasticity and resilience under varying environmental conditions.

N-Boc-diethanolamine

103898-11-9sc-253104
5 ml
$193.00
(0)

N-Boc-diethanolamine serves as an effective crosslinker due to its ability to form stable covalent bonds through its amine and alcohol functional groups. The presence of the Boc protecting group enhances its reactivity by facilitating selective deprotection under mild conditions. This compound exhibits unique hydrogen bonding capabilities, promoting network formation in polymer matrices. Its versatile structure allows for tailored modifications, influencing reaction kinetics and enhancing material properties.

1,8-Bis-maleimidotetraethyleneglycol

115597-84-7sc-208810
25 mg
$245.00
(0)

1,8-Bis-maleimidotetraethyleneglycol is a specialized crosslinker distinguished by its dual maleimide groups, which promote selective and efficient thiol conjugation. The tetraethylene glycol segment enhances the compound's hydrophilicity and chain flexibility, facilitating the formation of dynamic polymer networks. Its unique reactivity profile allows for controlled crosslinking kinetics, enabling the design of materials with specific mechanical and thermal properties tailored to diverse applications.

4-Azido-2,3,5,6-tetrafluorobenzoic Acid

122590-77-6sc-209954
100 mg
$320.00
(0)

4-Azido-2,3,5,6-tetrafluorobenzoic Acid serves as a versatile crosslinker, distinguished by its azide functionality that enables efficient click chemistry reactions. This compound exhibits unique reactivity with alkyne groups, facilitating the formation of stable triazole linkages. Its fluorinated structure enhances solubility and compatibility with various substrates, while the electron-withdrawing nature of the fluorine atoms can influence reaction kinetics and improve thermal stability in crosslinked networks.

N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate

126695-58-7sc-208056
sc-208056A
50 mg
100 mg
$193.00
$203.00
(0)

N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate serves as a versatile crosslinker, characterized by its azide functionality that enables efficient click chemistry reactions. The presence of multiple fluorine atoms enhances its lipophilicity and stability, promoting selective interactions with biomolecules. Its unique reactivity profile allows for rapid conjugation under mild conditions, facilitating the formation of stable linkages in complex systems, thus enabling precise control over molecular assembly and network formation.