Date published: 2025-9-12

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 111 to 120 of 345 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

ANP-Linker

171778-06-6sc-291904
sc-291904A
100 mg
5 g
$160.00
$839.00
(0)

ANP-Linker is a specialized crosslinker known for its unique reactivity as an acid halide, which facilitates the formation of stable covalent bonds through nucleophilic substitution. Its distinct molecular structure promotes selective interactions with amines and alcohols, leading to tailored crosslinking pathways. The linker exhibits rapid reaction kinetics, allowing for efficient network formation, while its solubility in various organic solvents enhances its versatility in diverse chemical systems.

[N-(2-Maleimidoethyl]diethylenetriaminepentaacetic Acid, Monoamide

180152-82-3sc-218918
10 mg
$500.00
(0)

N-(2-Maleimidoethyl)diethylenetriaminepentaacetic Acid, Monoamide serves as an effective crosslinker, distinguished by its ability to form stable complexes with metal ions through its chelating properties. The diethylenetriamine backbone enhances its reactivity, facilitating rapid crosslinking under mild conditions. This compound's unique structure promotes the formation of robust three-dimensional networks, improving the mechanical strength and thermal stability of the resulting materials.

4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid

181148-00-5sc-209848
10 mg
$330.00
(0)

4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid, serves as an effective crosslinker due to its unique hydrazide functionality, which facilitates the formation of stable hydrazone bonds. The cyclohexane structure imparts rigidity, enhancing the mechanical properties of the resulting network. Its trifluoroacetic acid component promotes solubility and reactivity, enabling efficient crosslinking under mild conditions, while the maleimidomethyl group allows for selective interactions with thiol-containing compounds, ensuring precise network formation.

4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt

67483-13-0sc-214282
sc-214282B
sc-214282A
25 mg
250 mg
100 mg
$120.00
$260.00
$117.00
1
(2)

4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt acts as a versatile crosslinker, characterized by its ability to form robust thiourea linkages through nucleophilic attack on isothiocyanate groups. This compound exhibits unique solubility properties, enhancing its compatibility with diverse polymer matrices. Its distinct electronic structure promotes selective interactions, leading to tailored network architectures and improved mechanical properties in crosslinked materials.

2-[2-(Fmoc-amino)ethoxy]ethylamine hydrochloride

221352-88-1sc-225114
500 mg
$136.00
(0)

2-[2-(Fmoc-amino)ethoxy]ethylamine hydrochloride acts as an effective crosslinker through its unique amino and ether functionalities. The Fmoc group provides a protective mechanism, allowing selective reactions with nucleophiles. This compound's ability to form stable amine linkages enhances network formation in polymer matrices. Its hydrophilic nature contributes to improved solubility and dispersion in various media, facilitating tailored material properties and structural integrity.

3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-azide

356046-26-9sc-206716
100 mg
$337.00
(0)

3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-azide serves as a versatile crosslinker, characterized by its unique ability to form robust networks through azide-alkyne cycloaddition reactions. The presence of multiple ether linkages enhances its flexibility and solubility in various solvents, promoting effective dispersion in polymer matrices. Its reaction kinetics are influenced by the density of azide groups, allowing for tunable crosslinking density and mechanical properties in the resulting materials.

3-Maleimidopropionic Acid Hydrazonium, Trifluoroacetate

359436-61-6sc-357610
25 mg
$320.00
(0)

3-Maleimidopropionic Acid Hydrazonium, Trifluoroacetate functions as a versatile crosslinker, characterized by its unique hydrazonium moiety that facilitates rapid and selective reactions with electrophiles. This compound enhances network formation through dynamic covalent bonding, promoting robust structural frameworks. Its trifluoroacetate component imparts increased stability and solubility in polar solvents, optimizing reaction conditions and expanding its utility in various polymer systems.

N-Succinimidyloxycarbonylethyl Methanethiosulfonate

385399-11-1sc-212284
10 mg
$360.00
(0)

N-Succinimidyloxycarbonylethyl Methanethiosulfonate acts as a versatile crosslinker, characterized by its methanethiosulfonate moiety that enables selective thiol-reactive crosslinking. This compound exhibits unique reactivity with thiols, leading to the formation of stable thioether bonds. Its distinct chemical structure allows for tunable crosslinking efficiency, facilitating the creation of robust networks. The compound's reaction kinetics are favorable, promoting rapid and efficient covalent bond formation in diverse applications.

Boc-O2Oc-OH*DCHA

560088-79-1sc-293924
sc-293924A
100 mg
500 mg
$109.00
$304.00
(0)

Boc-O2Oc-OH*DCHA serves as an effective crosslinker, characterized by its unique ability to engage in selective reactions with nucleophiles, leading to robust covalent bonds. Its distinct structure allows for tailored crosslinking pathways, enhancing the mechanical properties of polymer networks. The compound exhibits favorable reaction kinetics, promoting rapid formation of crosslinks, while its hydrophobic segments contribute to phase separation, influencing material properties and stability.

15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid

756525-91-4sc-287305
100 mg
$136.00
(0)

15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid functions as a versatile crosslinker, distinguished by its multiple ether linkages that facilitate the formation of stable networks. The presence of the Boc-protecting group enhances its reactivity, allowing for selective interactions with amine functionalities. This compound's unique structure promotes effective spatial arrangement in polymer systems, leading to improved mechanical integrity and resilience. Its reaction kinetics are influenced by the steric effects of the Boc group, enabling controlled crosslinking under specific conditions.