Date published: 2026-5-6

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 121 to 130 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

6-[2-Biotinylamidoethyl]-dithiopropionamido]-4,8-diaza-5,7-diketoundecanoic Acid, Bis-N-sulfosuccinimidyl Ester Disodium Salt

1044220-56-5sc-207084
1 mg
$330.00
(0)

6-[2-Biotinylamidoethyl]-dithiopropionamido]-4,8-diaza-5,7-diketoundecanoic Acid, Bis-N-sulfosuccinimidyl Ester Disodium Salt serves as a potent crosslinker, featuring a unique combination of biotinylation and dithiopropionamide functionalities. This structure promotes specific interactions with avidin or streptavidin, enabling robust conjugation. Its disodium salt form enhances solubility, facilitating efficient crosslinking in diverse environments, while the dithiopropionamide moiety allows for versatile reaction pathways, ensuring stable and effective linkage formation.

1-Acetyl-2,2,5,5-tetramethyl-3-pyrroline-3-carboxylic Acid N-Hydroxysuccinimide Ester

1076198-74-7sc-206120
10 mg
$330.00
(0)

1-Acetyl-2,2,5,5-tetramethyl-3-pyrroline-3-carboxylic Acid N-Hydroxysuccinimide Ester acts as a versatile crosslinker, notable for its ability to form stable amide bonds through nucleophilic attack by amines. The presence of the pyrroline ring enhances electron delocalization, influencing reaction kinetics and selectivity. Its unique structure allows for efficient coupling reactions, enabling the formation of intricate polymer networks with specific mechanical and thermal properties.

N1-Boc-2,2′-iminodiethylamine

193206-49-4sc-250545
sc-250545A
1 ml
5 ml
$63.00
$401.00
(0)

N1-Boc-2,2'-iminodiethylamine serves as an effective crosslinker, characterized by its unique bifunctional structure that promotes selective reactivity. The presence of the Boc protecting group enhances stability while allowing for controlled deprotection, facilitating targeted crosslinking. Its ability to form stable covalent bonds through nucleophilic attack enables the creation of intricate polymer networks. This compound's tunable reactivity and steric properties contribute to tailored material characteristics, optimizing performance in diverse applications.

(S)-1-(4-Aminoxyacetamidobenzyl)ethylenediaminetetraacetic Acid

1217704-71-6sc-220047
5 mg
$360.00
(0)

(S)-1-(4-Aminoxyacetamidobenzyl)ethylenediaminetetraacetic Acid acts as a versatile crosslinker, exhibiting strong chelating properties that enable it to form stable complexes with metal ions. Its unique functional groups facilitate multiple binding sites, promoting intricate network formation in polymer systems. The compound's ability to engage in hydrogen bonding and electrostatic interactions enhances its reactivity, allowing for controlled crosslinking and improved material stability.

1-Biotinylamino-3,6,9-trioxaundecane-11-ol

sc-213312
25 mg
$360.00
(0)

1-Biotinylamino-3,6,9-trioxaundecane-11-ol serves as an effective crosslinker due to its unique structural features that promote robust molecular interactions. The presence of biotin enhances affinity for avidin or streptavidin, facilitating strong and specific binding. Its trioxaundecane backbone provides flexibility, allowing for optimal spatial arrangement during crosslinking reactions. This compound's ability to form stable linkages under varying conditions makes it a versatile tool in polymer chemistry and material science.

[Biotinylamidoethyl]-dithiomethylenemalonic Acid Bis(2-aminoethanoic Acid)

sc-221363
5 mg
$300.00
(0)

[Biotinylamidoethyl]-dithiomethylenemalonic Acid Bis(2-aminoethanoic Acid) serves as an innovative crosslinker, distinguished by its dual functionality and the presence of dithiomethylene groups. This compound promotes selective thiol-disulfide exchange reactions, enabling precise control over polymer network formation. Its unique structural features facilitate the development of intricate three-dimensional architectures, enhancing mechanical properties and enabling dynamic responsiveness in various environments.

2-[N2-(N6-t-Boc-6-aminocaproyl)-N6-(6-biotinamidocaproy)-L -lysinylamido]ethyl Methanethiosulfonate

sc-223339
5 mg
$280.00
(0)

2-[N2-(N6-t-Boc-6-aminocaproyl)-N6-(6-biotinamidocaproy)-L-lysinylamido]ethyl Methanethiosulfonate serves as a specialized crosslinker, notable for its ability to form stable thioether bonds. The presence of biotin and t-Boc groups facilitates selective interactions, promoting targeted conjugation in complex systems. Its unique structure allows for controlled reaction kinetics, enabling precise modulation of crosslink density and enhancing the mechanical properties of assembled materials.

1,10-Decadiyl Bismethanethiosulfonate

56-02-0sc-208713
25 mg
$360.00
(1)

1,10-Decadiyl Bismethanethiosulfonate acts as a versatile crosslinker, engaging in dynamic thiol-ene reactions that yield intricate polymer architectures. Its elongated carbon chain enhances flexibility and compatibility with various substrates, while its dual reactive sites promote efficient network formation. The compound's unique ability to facilitate multiple crosslinking pathways allows for fine-tuning of material properties, such as elasticity and durability, making it a significant contributor to advanced polymer systems.

N-(2-Bromoethyl)phthalimide

574-98-1sc-250424
25 g
$43.00
(0)

N-(2-Bromoethyl)phthalimide acts as an effective crosslinker, distinguished by its ability to engage in nucleophilic substitution reactions due to the electrophilic nature of the bromoethyl group. This compound's phthalimide moiety contributes to its stability and enhances the formation of crosslinked networks, leading to improved material integrity. Its reactivity profile allows for controlled polymerization kinetics, enabling the customization of physical properties such as elasticity and thermal resistance in various applications.

1,11-Diamino-3,6,9-trioxaundecane

929-75-9sc-253958
sc-253958A
sc-253958B
100 mg
250 mg
1 g
$163.00
$239.00
$285.00
(0)

1,11-Diamino-3,6,9-trioxaundecane functions as a versatile crosslinker, characterized by its unique trioxaundecane backbone that introduces ether linkages. These linkages enhance molecular flexibility and facilitate complex interactions with polymer chains, promoting effective network formation. The compound's ability to form multiple hydrogen bonds allows for increased thermal stability and mechanical strength in crosslinked materials, while its hydrophilic segments improve compatibility with various substrates, ensuring uniform distribution and enhanced performance in diverse applications.