Galanin Activators
Galanin activators encompass a diverse range of chemicals, each with unique biochemical properties and modes of action within cellular pathways. These activators, despite their varied nature, converge in their potential to influence the activity or expression of the protein Galanin in neuronal or other cellular environments. This influence is mediated through direct or indirect interactions with signaling pathways intimately connected with Galanin's functional landscape.
For instance, compounds such as cyclic AMP and Forskolin function through the modulation of the cAMP-dependent pathway, a critical signaling cascade in cellular communication. By enhancing cAMP levels, these activators can activate protein kinase A (PKA), a pivotal enzyme in phosphorylating various substrates within the cell. This phosphorylation can lead to alterations in gene expression or protein function, which may include the modulation of Galanin. Similarly, other activators like Phorbol 12-myristate 13-acetate (PMA) and Lithium chloride act through different but equally significant pathways. PMA's activation of protein kinase C (PKC) and Lithium's impact on the phosphoinositide signaling pathway exemplify the diverse mechanisms through which Galanin activity can be influenced. These pathways, integral to numerous cellular processes, offer a conduit through which Galanin's role in the cell can be modulated.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
Cyclic AMP is a second messenger important in many biological processes. It activates protein kinase A (PKA), which can phosphorylate various targets in the cell, potentially influencing the activity of galanin. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin directly activates adenylate cyclase, increasing levels of cAMP and subsequently activating PKA. This activation may influence the expression or function of galanin. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which is involved in numerous signaling pathways. PKC activation can modulate neurotransmitter release and may indirectly affect galanin signaling. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium affects the phosphoinositide signaling pathway, which is linked to mood regulation and neuronal activity. This alteration may indirectly influence galanin expression or function. | ||||||
(±)-Norepinephrine (+)-bitartrate salt | 3414-63-9 | sc-255396 | 1 g | $112.00 | ||
As a neurotransmitter, norepinephrine can activate adrenergic receptors, which might modulate galanin levels or activity in neurons. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Estrogen can modulate neuronal function and neuroplasticity, potentially affecting galanin expression or activity in certain brain regions. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $42.00 $83.00 $155.00 | 7 | |
Nitric oxide acts as a neurotransmitter and neuromodulator and can influence neuronal signaling pathways, potentially impacting galanin activity. | ||||||
(±)-Baclofen | 1134-47-0 | sc-200464 sc-200464A | 1 g 5 g | $55.00 $253.00 | ||
GABAergic signaling can modulate various neuronal pathways, potentially influencing galanin expression or function in the brain. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $291.00 $566.00 | ||
As the main excitatory neurotransmitter in the CNS, glutamate can modulate neuronal activity and signaling pathways, potentially affecting galanin levels or activity. | ||||||
Serotonin hydrochloride | 153-98-0 | sc-201146 sc-201146A | 100 mg 1 g | $116.00 $183.00 | 15 | |
Serotonin, through its diverse receptors, can modulate numerous neuronal pathways, potentially impacting galanin signaling. | ||||||